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Article
Association of sleep fragmentation with general and abdominal obesity: a population-based longitudinal study
To evaluate the causal relationship between sleep fragmentation (SF) parameters with general and abdominal obesity in free-living conditions.
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Article
Radio-frequency Identification (RFID) adoption and chain structure decisions in competing supply chains: Bertrand competition versus Cournot competition
We investigate the RFID adoption and chain structure (i.e., integrated or decentralized) decisions in two supply chains under two competition modes (i.e., Bertrand or Cournot competition). Each chain consists ...
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Article
Open AccessAn integrated data analysis reveals distribution, hosts, and pathogen diversity of Haemaphysalis concinna
Haemaphysalis concinna, carrying multiple pathogens, has attracted increasing attention because of its expanded geographical range and significant role in disease transmission. This study aimed to identify the po...
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Article
Open AccessEpidemiological behaviour and interventions of malaria in Niger, 2010–2019: a time-series analysis of national surveillance data
Malaria remains a significant public health concern in Niger, with the number of cases increasing from 592,334 in 2000 to 3,138,696 in 2010. In response, a concerted campaign against the disease has been initi...
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Article
Open AccessComorbidity increases the risk of pulmonary tuberculosis: a nested case-control study using multi-source big data
Some medical conditions may increase the risk of develo** pulmonary tuberculosis (PTB); however, no systematic study on PTB-associated comorbidities and comorbidity clusters has been undertaken.
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Article
Open AccessImmunomodulation of cuproptosis and ferroptosis in liver cancer
According to statistics, the incidence of liver cancer is increasing yearly, and effective treatment of liver cancer is imminent. For early liver cancer, resection surgery is currently the most effective treat...
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Article
Open AccessSystematic review and integrated data analysis reveal diverse pangolin-associated microbes with infection potential
There has been increasing global concern about the spillover transmission of pangolin-associated microbes. To assess the risk of these microbes for emergence as human pathogens, we integrated data from multipl...
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Article
Spatiotemporal distribution of regional landslides and erosion rates in Southeastern Tibet
The difficulty in estimating ages of regional landslides hampers to assess frequency of landslides and hence to quantitatively assess regional landslide hazard. In this study, we used radiocarbon dating of org...
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Article
Open AccessCirculating Irisin Level as a Biomarker for Pure Aortic Stenosis and Aortic Valve Calcification
Irisin, a myokine mainly secreted by skeletal and cardiac muscles, is actively involved in cardiovascular diseases. However, whether irisin is associated with aortic stenosis remains unknown. Two hundred ninet...
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Article
Open AccessAntimicrobial activity and comparative metabolomic analysis of Priestia megaterium strains derived from potato and dendrobium
The growth of endophytic bacteria is influenced by the host plants and their secondary metabolites and activities. In this study, P. megaterium P-NA14 and P. megaterium D-HT207 were isolated from potato tuber and...
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Article
Association of placental PPARα/γ and miR-27b expression with macrosomia in healthy pregnancy
Peroxisomal proliferator-activated receptors (PPARs) and microRNAs (miRNAs) play important roles in the development of fetuses, whereas expression changes of PPARs and three miRNAs (miR-17, miR-27b and miR-34a...
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Article
Open AccessBenefits from the first year of GnRHa therapy in boys with idiopathic central precocious puberty when initiating treatment after age 9 years: findings from a real-world retrospective study
GnRHa treatment was established for improving final adult height (FAH) in children presenting with Idiopathic central precocious puberty (ICPP) up to age 8, while several controversies remained for older age g...
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Article
Open AccessAutomated classification of protein expression levels in immunohistochemistry images to improve the detection of cancer biomarkers
The expression changes of some proteins are associated with cancer progression, and can be used as biomarkers in cancer diagnosis. Automated systems have been frequently applied in the large-scale detection of...
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Article
Starch, cellulose and plant extracts as green inhibitors of metal corrosion: a review
Traditional corrosion inhibitors have made great contributions to metal corrosion protection. However, environmental pollution caused by them is becoming more serious. To circumvent this tricky problem, green ...
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Article
Open AccessEnsemble learning for predicting ex vivo human placental barrier permeability
The placental barrier protects the fetus from exposure to some toxicants and is vital for drug development and risk assessment of environmental chemicals. However, in vivo experiments for assessing the placent...
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Article
Associations between seasonal ambient air pollution and adverse perinatal outcomes: a retrospective cohort study in Wenzhou, China
Prenatal exposure to ambient air pollution has been associated with adverse perinatal outcomes in previous studies. However, few studies have examined the interaction between air pollution and the season of co...
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Article
Strategic analysis of RFID adoption sequences in a supply chain with Cournot competition: effects of ordering-timing strategies
We investigate the effects of ordering-timing strategies on radio-frequency identification (RFID) adoption sequences and firms’ profitability in a supply chain with a manufacturer and two retailers, both of wh...
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Article
Chinese Medicine Meets Conventional Medicine in Targeting COVID-19 Pathophysiology, Complications and Comorbidities
To investigate how the National Health Commission of China (NHCC)-recommended Chinese medicines (CMs) modulate the major maladjustments of coronavirus disease 2019 (COVID-19), particularly the clinically obser...
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Article
Open AccessProfile and dynamics of infectious diseases: a population-based observational study using multi-source big data
The current surveillance system only focuses on notifiable infectious diseases in China. The arrival of the big-data era provides us a chance to elaborate on the full spectrum of infectious diseases.
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Article
Open AccessImaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer’s disease
Discovery of early-stage biomarkers is a long-sought goal of Alzheimer’s disease (AD) diagnosis. Age is the greatest risk factor for most AD and accumulating evidence suggests that age-dependent elevation of a...
