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Article

Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress

Aberrant DNA hypermethylation is frequently found in tumor cells and inhibition of DNA methylation is an effective anticancer strategy. In this study, the therapeutic effect of DNA methyltransferase (DNMT) inh...

Pei-Ming Yang, Yi-Ting Lin, Chia-Tung Shun, Shan-Hu Lin, Tzu-Tang Wei… in Scientific Reports (2013)