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  1. Article

    Open Access

    In vitro infection of bovine erythrocytes with Theileria annulata merozoites as a key step in completing the T. annulata life cycle in vitro

    Theileria annulata is a protozoan parasite with a complex life cycle involving a bovine host and a tick vector. It is transmitted by Hyalomma ticks and is the causative agent of tropical theileriosis, a debilitat...

    Khawla Elati, Shahin Tajeri, Robert M. Mugo, Isaiah Obara in Scientific Reports (2024)

  2. Article

    Open Access

    Dual RNA-seq to catalogue host and parasite gene expression changes associated with virulence of T. annulata-transformed bovine leukocytes: towards identification of attenuation biomarkers

    The apicomplexan parasite Theileria annulata is transmitted by Hyalomma ticks and causes an acute lymphoproliferative disease that is invariably lethal in exotic cattle breeds. The unique ability of the schizont ...

    Khawla Elati, Shahin Tajeri, Isaiah Obara, Moez Mhadhbi in Scientific Reports (2023)

  3. Article

    Open Access

    Theileria annulata histone deacetylase 1 (TaHDAC1) initiates schizont to merozoite stage conversion

    A fungal metabolite, FR235222, specifically inhibits a histone deacetylase of the apicomplexan parasite Toxoplasma gondii and TgHDAC3 has emerged as a key factor regulating developmental stage transition in this ...

    Shahin Tajeri, Laurence Momeux, Benjamin Saintpierre, Sara Mfarrej in Scientific Reports (2022)