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Article
Femtosecond laser microdissection for isolation of regenerating C. elegans neurons for single-cell RNA sequencing
Our understanding of nerve regeneration can be enhanced by delineating its underlying molecular activities at single-neuron resolution in model organisms such as Caenorhabditis elegans. Existing cell isolation te...
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Article
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy
Neoantigens are peptides derived from non-synonymous mutations presented by human leukocyte antigens (HLAs), which are recognized by antitumour T cells1–14. The large HLA allele diversity and limiting clinical sa...
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Article
Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4
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Article
Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4
Amyotrophic lateral sclerosis (ALS) is a heterogenous neurodegenerative disorder that affects motor neurons and voluntary muscle control1. ALS heterogeneity includes the age of manifestation, the rate of progress...