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    Article

    Femtosecond laser microdissection for isolation of regenerating C. elegans neurons for single-cell RNA sequencing

    Our understanding of nerve regeneration can be enhanced by delineating its underlying molecular activities at single-neuron resolution in model organisms such as Caenorhabditis elegans. Existing cell isolation te...

    Peisen Zhao, Sudip Mondal, Chris Martin, Andrew DuPlissis, Shahab Chizari in Nature Methods (2023)

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    Article

    Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy

    Neoantigens are peptides derived from non-synonymous mutations presented by human leukocyte antigens (HLAs), which are recognized by antitumour T cells114. The large HLA allele diversity and limiting clinical sa...

    Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L. Wang, Zheng Pan in Nature (2023)

  3. Article

    Author Correction: Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4

    Laura Campisi, Shahab Chizari, Jessica S. Y. Ho, Anastasia Gromova in Nature (2022)

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    Article

    Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4

    Amyotrophic lateral sclerosis (ALS) is a heterogenous neurodegenerative disorder that affects motor neurons and voluntary muscle control1. ALS heterogeneity includes the age of manifestation, the rate of progress...

    Laura Campisi, Shahab Chizari, Jessica S. Y. Ho, Anastasia Gromova in Nature (2022)