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Article
A community effort to create standards for evaluating tumor subclonal reconstruction
Tumor DNA sequencing data can be interpreted by computational methods that analyze genomic heterogeneity to infer evolutionary dynamics. A growing number of studies have used these approaches to link cancer ev...
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Open AccessCombining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection
The phenotypes of cancer cells are driven in part by somatic structural variants. Structural variants can initiate tumors, enhance their aggressiveness, and provide unique therapeutic opportunities. Whole-geno...
