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Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins
T cell infiltration into tumors is a favorable prognostic feature, but most solid tumors lack productive T cell responses. Mechanisms that coordinate T cell exclusion are incompletely understood. Here we ident...
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Article
Open AccessKupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice
Although macrophages contribute to cancer cell dissemination, immune evasion, and metastatic outgrowth, they have also been reported to coordinate tumor-specific immune responses. We therefore hypothesized tha...
