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Article
Open AccessThe role of cytoreductive nephrectomy in metastatic renal cell carcinoma in immune-oncology era (SEVURO-CN): study protocol for a multi-center, prospective, randomized trial
The role of cytoreductive nephrectomy (CN) in the treatment of metastatic renal cell carcinoma (mRCC) remains unclear in the immuno-oncology (IO) era. The results of two randomized trials, CARMENA and SURTIME,...
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Article
Open AccessInitiation of the Unazuki Belt, Southwest Japan, during the Carboniferous as an island arc system along the North China Craton
The Unazuki Belt, Southwest Japan, is a part of the Hida Belt, which is characterized as a plutono-metamorphic complex with a continental affinity formed between the late Paleozoic and early Mesozoic. The Unaz...
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Article
Open AccessDecision regret after prostate biopsy for prostate cancer diagnosis: a Korean multicenter cohort study
Many people struggle with the choice in a series of processes, from prostate cancer (PCa) diagnosis to treatment. We investigated the degree of regret after the prostate biopsy (PBx) and relevant factors in pa...
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Article
Highly efficient and specific regulation of gene expression using enhanced CRISPR-Cas12f system
The recently developed CRISPR activator (CRISPRa) system uses a CRISPR-Cas effector-based transcriptional activator to effectively control the expression of target genes without causing DNA damage. However, ex...
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Article
Open AccessDepressive symptoms of people living in areas with high exposure to environmental noise: a multilevel analysis
Exposure and damage caused by noise have been reported in many countries around the world. However, few nationwide studies explored the association of residential environmental noise with depressive symptoms, ...
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Article
Electrospinning and electrospraying of polybutylene succinate/esterified cellulose nanofibril composites
Cellulose nanofibrils (CNF) were esterified using long-chain fatty acid chlorides (octanoyl chloride, lauroyl chloride, and palmitoyl chloride) and composited with a biodegradable polymer, polybutylene succina...
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Article
Open AccessAuthor Correction: Effects of boiling water treatment on the physical properties of Quercus variabilis virgin cork grown in Korea
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Article
Open AccessBlood vessel organoids generated by base editing and harboring single nucleotide variation in Notch3 effectively recapitulate CADASIL-related pathogenesis
Human blood vessel organoids (hBVOs) offer a promising platform for investigating vascular diseases and identifying therapeutic targets. In this study, we focused on in vitro modeling and therapeutic target findi...
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Article
Influence of Borehole Shear Test Wedge Spacing on Shear Strength Parameters of Intermediate Geomaterials
The borehole shear test (BST) is an in-situ test method to estimate shear strength and its parameters of geomaterials (i.e., cohesion and friction angle). The shear plate with wedges is an important component of ...
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Article
A prognostic value of estimated pulse wave velocity in idiopathic sudden sensorineural hearing loss
Arterial stiffness, represented by estimated pulse wave velocity (ePWV), is the independent surrogate marker for cardiovascular event. The aim of the study was to investigate the significance of ePWV in the tr...
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Article
Open AccessAssessing the accuracy and reliability of application-based audiometry for hearing evaluation
Pure-tone audiometry (PTA) is the gold standard for assessing hearing loss. However, traditional PTA tests require specialized equipment, trained personnel, and a soundproof environment. Recently, smartphone-b...
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Article
Open AccessEvaluating a combination treatment of NK cells and reovirus against bladder cancer cells using an in vitro assay to simulate intravesical therapy
Intravesical treatment using either reovirus or natural killer (NK) cells serves as an efficient strategy for the treatment of bladder cancer cells (BCCs); however, corresponding monotherapies have often shown...
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Article
Quantification of tremor dynamics via video-based analysis
Tremor is a common movement disorder diagnosed employing electrophysiological methods. Today, machine learning (ML) algorithms can efficiently analyze image-based data. Thus, we subjected the dynamics of essen...
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Article
Open AccessEffects of boiling water treatment on the physical properties of Quercus variabilis virgin cork grown in Korea
The effects of boiling water treatment on the physical properties of Quercus variabilis virgin cork (Qv VC) were examined and compared with those of Quercus suber reproduction cork (Qs RC). The water treatment wa...
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Article
Statistical integration of allele frequencies from several organizations
Genetic evidence, especially evidence based on short tandem repeats, is of paramount importance for human identification in forensic inferences. In recent years, the identification of kinship using DNA evidenc...
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Article
Open AccessUtilization of nicking properties of CRISPR-Cas12a effector for genome editing
The CRISPR-Cas nickase system for genome editing has attracted considerable attention owing to its safety, efficiency, and versatility. Although alternative effectors to Cas9 have the potential to expand the s...
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Article
Environmental-, social-, and governance-related factors for business investment and sustainability: a scientometric review of global trends
Consideration of environmental, social, and governance (ESG) factors can contribute to the environmental and economic performance of organizations in terms of investment and sustainability. This article thorou...
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Article
Open AccessPublisher Correction: Risk of data leakage in estimating the diagnostic performance of a deep-learning-based computer-aided system for psychiatric disorders
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Article
X-ray diffraction, Fourier transform infrared spectroscopy, and thermal decomposition analyses of virgin cork elements in Quercus variabilis grown in Korea
The crystalline characteristics, chemical composition, and thermal decomposition of elements in Quercus variabilis (Qv) virgin cork were investigated using X-ray diffraction, Fourier transform infrared spectrosco...
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Article
Open AccessDurability of heat-treated Paulownia tomentosa and Pinus koraiensis woods in palm oil and air against brown- and white-rot fungi
This study aimed to evaluate and compare the effects of oil- and air-heat treatments on the durability of Paulownia tomentosa and Pinus koraiensis woods against Fomitopsis palustris and Trametes versicolor. The w...
