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Open AccessChoroid plexus carcinoma with leptomeningeal spread in an adult: a case report and review of the literature
Choroid plexus carcinoma is an intraventricular neoplasm originating from the choroid plexus epithelium and is of rare occurrence in adults. However, owing to the low prevalence of choroid plexus carcinoma, th...
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Article
Open AccessIsoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents
Among the enzymes involved in the post-translational modification of Ras, isoprenyl carboxyl methyltransferase (ICMT) has been explored by a number of researchers as a significant enzyme controlling the activa...
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Article
Open AccessClinical utility of pretreatment prediction of chemoradiotherapy response in rectal cancer: a review
Approximately 20% of all patients with locally advanced rectal cancer experience pathologically complete responses following neoadjuvant chemoradiotherapy (CRT) and standard surgery. The utility of radical sur...
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Article
Open AccessLow-mass-ion discriminant equation (LOME) for ovarian cancer screening
A low-mass-ion discriminant equation (LOME) was constructed to investigate whether systematic low-mass-ion (LMI) profiling could be applied to ovarian cancer (OVC) screening.
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Article
Open AccessIs elective inguinal radiotherapy necessary for locally advanced rectal adenocarcinoma invading anal canal?
We investigated whether routine elective irradiation of a clinically negative inguinal node (IGN) is necessary for patients with locally advanced distal rectal cancer and anal canal invasion (ACI).
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Article
Open AccessPatterns of failure in patients with locally advanced rectal cancer receiving pre-operative or post-operative chemoradiotherapy
We investigated patterns of failure in patients with locally advanced rectal cancer (LARC) according to chemoradiotherapy (CRT) timing: pre-operative versus post-operative. Also, patterns of failure, particularly...
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Article
Open AccessUp-regulated expression of l-caldesmon associated with malignancy of colorectal cancer
Caldesmon (CaD), a major actin-associated protein, is found in smooth muscle and non-muscle cells. Smooth muscle caldesmon, h-CaD, is a multifunctional protein, and non-muscle cell caldesmon, l-CaD, plays a role ...
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Article
Open AccessWhole-liver radiotherapy for end-stage colorectal cancer patients with massive liver metastases and advanced hepatic dysfunction
To investigate whether whole-liver radiotherapy (RT) is beneficial in end-stage colorectal cancer with massive liver metastases and severe hepatic dysfunction.
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Open AccessAccelerated partial breast irradiation using multicatheter brachytherapy for select early-stage breast cancer: local control and toxicity
To investigate the efficacy and safety of accelerated partial breast irradiation (APBI) via high-dose-rate (HDR) multicatheter interstitial brachytherapy for early-stage breast cancer.