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  1. Article

    Open Access

    Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling

    M2-like tumor-associated macrophages (TAMs) are risk factors for cancer progression and metastasis. However, the mechanisms underlying their polarization are still not fully understood. Although cathepsin D (C...

    Seul Gi Lee, Seon Min Woo, Seung Un Seo in Experimental & Molecular Medicine (2024)

  2. No Access

    Article

    Association between urinary arsenic concentration and genetic polymorphisms in Korean adults

    Arsenic (As) is a human carcinogen widely distributed in the environment. This study evaluated the association between the urinary As concentration and single nucleotide polymorphisms (SNPs) in Korean adults t...

    Seul-Gi Lee, Sang-Yong Eom, Ji-Ae Lim, Byung-Sun Choi in Toxicological Research (2024)

  3. Article

    Open Access

    TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway

    Extracellular matrix proteins are associated with metabolically healthy adipose tissue and regulate inflammation, fibrosis, angiogenesis, and subsequent metabolic deterioration. In this study, we demonstrated ...

    Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo in Experimental & Molecular Medicine (2023)

  4. Article

    Post-Marketing Pooled Safety Analysis for CT-P13 Treatment of Patients with Immune-Mediated Inflammatory Diseases in Observational Cohort Studies

    At EU marketing authorisation, safety data for CT-P13 (biosimilar infliximab) were limited, particularly in some indications, and uncommon adverse events (AEs) could not be evaluated among relatively small ana...

    Sang Joon Lee, KyungMin Baek, Su** Lee, Yoon Jee Lee, Jeong Eun Park in BioDrugs (2020)