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  1. Article

    Open Access

    CREB5 promotes the proliferation and self-renewal ability of glioma stem cells

    Glioblastoma multiforme (GBM) is the most fatal form of brain cancer in humans, with a dismal prognosis and a median overall survival rate of less than 15 months upon diagnosis. Glioma stem cells (GSCs), have ...

    Hyun-** Kim, Hye-Min Jeon, Don Carlo Batara, Seongsoo Lee in Cell Death Discovery (2024)

  2. No Access

    Article

    Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning

    Simultaneous imaging of various facets of intact biological systems across multiple spatiotemporal scales is a long-standing goal in biology and medicine, for which progress is hindered by limits of convention...

    YoungJu Jo, Hyungjoo Cho, Wei Sun Park, Geon Kim, DongHun Ryu in Nature Cell Biology (2021)

  3. Article

    Open Access

    Detection of intracellular monosodium urate crystals in gout synovial fluid using optical diffraction tomography

    Optical diffraction tomography (ODT) enables imaging of unlabeled intracellular components by measuring the three-dimensional (3D) refractive index (RI). We aimed to detect intracellular monosodium urate (MSU)...

    Sangwoo Park, Lucy Eunju Lee, Hanna Kim, Ji Eun Kim, Seung Jun Lee in Scientific Reports (2021)

  4. Article

    Open Access

    The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response

    Cytoplasmic inclusions of transactive response DNA binding protein of 43 kDa (TDP-43) in neurons and astrocytes are a feature of some neurodegenerative diseases, such as frontotemporal lobar degeneration with ...

    Shinrye Lee, Seyeon Kim, Ha-Young Kang, Hye Ryeong Lim in Journal of Neuroinflammation (2020)

  5. No Access

    Reference Work Entry In depth

    Miro (Mitochondrial Rho)

    Seongsoo Lee, Kun-Sun Lee, Sungun Huh, Bingwei Lu in Encyclopedia of Signaling Molecules (2018)

  6. Article

    Open Access

    Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer’s disease treatment

    Alzheimer’s disease (AD) is a neurodegenerative disease characterized by genotypic and phenotypic heterogeneity. Critical components of the two AD pathological pathways, Aβ-amyloidosis and Tauopathy, have been...

    Wenchao Sun, Seongsoo Lee, **aoran Huang, Song Liu in Scientific Reports (2016)

  7. No Access

    Living Reference Work Entry In depth

    Miro (Mitochondrial Rho)

    Seongsoo Lee, Kun-Sun Lee, Sungun Huh, Bingwei Lu in Encyclopedia of Signaling Molecules

  8. Article

    Erratum to: Vision-Based Kidnap Recovery with SLAM for Home Cleaning Robots

    Seongsoo Lee, Sukhan Lee, Seungmin Baek in Journal of Intelligent & Robotic Systems (2015)

  9. No Access

    Article

    Phospho-dependent ubiquitination and degradation of PAR-1 regulates synaptic morphology and tau-mediated Aβ toxicity in Drosophila

    The conserved kinases PAR-1/MARK are critically involved in processes such as asymmetric cell division, cell polarity and neuronal differentiation. Their deregulation has been implicated in diseases including ...

    Seongsoo Lee, Ji-Wu Wang, Wendou Yu, Bingwei Lu in Nature Communications (2012)

  10. No Access

    Article

    Vision-Based Kidnap Recovery with SLAM for Home Cleaning Robots

    Emerged as salient in the recent home appliance consumer market is a new generation of home cleaning robot featuring the capability of Simultaneous Localization and Map** (SLAM). SLAM allows a cleaning robot...

    Seongsoo Lee, Sukhan Lee, Seungmin Baek in Journal of Intelligent & Robotic Systems (2012)

  11. No Access

    Article

    On a component mode synthesis on multi-level and its application to dynamics analysis of vehicle system supported with spring-stiffness damper system

    The component mode synthesis (CMS) method on multi-level, called as recursive component mode synthesis (RCMS) method, is implemented for the free vibration analysis of a vehicle system supported on damper-cont...

    Seongsoo Lee, Hyungsoo Mok, Chang-Wan Kim in Journal of Mechanical Science and Technology (2011)

  12. No Access

    Article

    The phosphoinositide phosphatase Sac1 is required for midline axon guidance

    Sac1 phosphoinositide (PI) phosphatases are important regulators of PtdIns(4)P turnover at the ER, Golgi, and plasma membrane (PM) and are involved in diverse cellular processes including cytoskeletal organiza...

    Seongsoo Lee, Sungdae Kim, Minyeop Nahm, Euijae Kim, Tai-Il Kim in Molecules and Cells (2011)

  13. No Access

    Chapter and Conference Paper

    Low-Power H.264 Deblocking Filter Algorithm and Its SoC Implementation

    This paper proposed a low-power H.264 deblocking filter algorithm. In H.264 deblocking filter, filtering can be skipped on some pixels when pixel differences satisfy some specific conditions. Furthermore, whol...

    Byung-Joo Kim, Jae-Il Koo, Min-Cheol Hong in Advances in Image and Video Technology (2006)

  14. No Access

    Chapter and Conference Paper

    Low-Power MPEG-4 Motion Estimator Design for Deep Sub-Micron Multimedia SoC

    This paper proposes novel low-power MPEG-4 motion estimator with deep submicron technologies below 0.13μm. The proposed motion estimator reduces both dynamic and static power consumption so that it is suitable...

    Gyu-Sung Yeon, Chi-Hun Jun, Tae-** Hwang in Knowledge-Based Intelligent Information an… (2005)

  15. No Access

    Chapter and Conference Paper

    Effective Directory Services and Classification Systems for Korean Language Education Internet Portal Sites

    Recently, the progress of information and communication technologies leads to web-based education. However, one of these problems is that it is very difficult to find out proper educational materials over the ...

    Su-** Cho, Seongsoo Lee in Advances in Intelligent Computing (2005)

  16. No Access

    Chapter and Conference Paper

    Pipelined Bidirectional Bus Architecture for Embedded Multimedia SoCs

    This paper proposes novel high-performance bus architecture for memory-intensive embedded multimedia SoCs. It has a pipelined bidirectional bus for high speed and small area. It has two separate bus called sys...

    Gang-Hoon Seo, Won-Yong Jung, Seongsoo Lee in Embedded and Ubiquitous Computing – EUC 20… (2005)

  17. No Access

    Chapter and Conference Paper

    Low-Power 32bit×32bit Multiplier Design with Pipelined Block-Wise Shutdown

    This paper proposes a novel low-power 32bit×32bit multiplier with pipelined block-wise shutdown scheme. When it idles, it turns off supply voltage to reduce both dynamic and static power. It shutdowns and wake...

    Yong-Ju Jang, Yoan Shin, Min-Cheol Hong in High Performance Computing – HiPC 2005 (2005)

  18. No Access

    Chapter and Conference Paper

    MOLEAS: Information Technology-Based Educational Software Framework

    Recently, the advent of Internet introduced E-learning, although there are still many practical problems to be solved. This paper presents an educational software framework based on the information technologie...

    Su-** Cho, Seongsoo Lee in Knowledge-Based Intelligent Information and Engineering Systems (2005)

  19. No Access

    Chapter and Conference Paper

    Low-Power Video Decoding for Mobile Multimedia Applications

    This paper proposes a novel low-power video decoding scheme. In the encoded video bitstream, there are quite a large number of non-coded blocks. When the number of the non-coded blocks in a frame is known at t...

    Seongsoo Lee, Min-Cheol Hong in Advances in Multimedia Information Processing - PCM 2004 (2005)

  20. No Access

    Chapter and Conference Paper

    Reliability Evaluation for an Oxygen Generator in an Air-conditioner by Accelerated Life Testing

    The oxygen generators in air-conditioners separate oxygen gas from air under high pressure by PSA (Pressure Swing Adsorption) method. The equipment was newly developed and there were not enough reliability tes...

    Yuri Jo, Sangjun Park, Seongsoo Lee in Probabilistic Safety Assessment and Manage… (2004)

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