74 Result(s)
within
Seong-** Yu
Life Sciences
English
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Article
Proxiome assembly of the plant nuclear pore reveals an essential hub for gene expression regulation
The nuclear pore complex (NPC) is vital for nucleocytoplasmic communication. Recent evidence emphasizes its extensive association with proteins of diverse functions, suggesting roles beyond cargo transport. Ye...
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Open AccessDPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson’s disease
Epidemiological studies report an elevated risk of Parkinson's disease (PD) in patients with type 2 diabetes mellitus (T2DM) that is mitigated in those prescribed dipeptidyl peptidase 4 (DPP-4) inhibitors. Wit...
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Open AccessSitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders
The endogenous incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) possess neurotrophic, neuroprotective, and anti-neuroinflammatory actions. The dipeptidyl peptida...
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Enhancing polyethylene degradation: a novel bioprocess approach using Acinetobacter nosocomialis pseudo-resting cells
Despite the discovery of several bacteria capable of interacting with polymers, the activity of the natural bacterial isolates is limited. Furthermore, there is a lack of knowledge regarding the development of...
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Open AccessIncreased urinary creatinine during hibernation and day roosting in the Eastern bent-winged bat (Miniopterus fuliginosus) in Korea
Torpor and arousal cycles, both daily and seasonal (e.g. hibernation), are crucial for small mammals, including bats, to maintain the energy and water balance. The alternation between torpor and arousal leads ...
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Article
Optimization conditions for cryopreservation of Nelumbo nucifera Gaertn., aquatic plant
This study was conducted to find the optimal cryopreservation conditions for efficiently preserving the genetic resources of the aquatic plant lotus (Nelumbo nucifera Gaertn). The seed viability differed dependin...
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Open AccessAuthor Correction: Keratin-mediated hair growth and its underlying biological mechanism
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Open AccessPublisher Correction: Keratin-mediated hair growth and its underlying biological mechanism
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Open AccessKeratin-mediated hair growth and its underlying biological mechanism
Here we show that intradermal injection of keratin promotes hair growth in mice, which results from extracellular interaction of keratin with hair forming cells. Extracellular application of keratin induces co...
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Article
Rasiella rasia gen. nov. sp. nov. within the family Flavobacteriaceae isolated from seawater recirculating aquaculture system
A novel bacterium designated RR4-40T was isolated from a biofilter of seawater recirculating aquaculture system in Busan, South Korea. Cells are strictly aerobic, Gram-negative, irregular short rod, non-motile, a...
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Open AccessEffects of smoking on the tissue regeneration-associated functions of human endometrial stem cells via a novel target gene SERPINB2
Smokers directly inhale mainstream cigarette smoke, which contains numerous known and potential toxic substances, and thus, smoking is expected to have broad harmful effects that cause tissue injury and dysfun...
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Open AccessLaboratory information management system for COVID-19 non-clinical efficacy trial data
As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus dis...
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Open AccessProbiotic potential of Tetragenococcus halophilus EFEL7002 isolated from Korean soy Meju
Probiotic starters can improve the flavor profile, texture, and health-promoting properties of fermented foods. Tetragenococcus halophilus is a halophilic lactic acid bacterium that is a candidate starter for hig...
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A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism
The potential use of biological agents has become a major public health concern worldwide. According to the CDC classification, Bacillus anthracis and Clostridium botulinum, the bacterial pathogens that cause ant...
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Article
OsPUB41, a U-box E3 ubiquitin ligase, acts as a negative regulator of drought stress response in rice (Oryza Sativa L.)
OsPUB41 plays a negative role in drought stress response through the mediation of OsUBC25 and interacts with OsCLC6, suggesting a putative substrate.
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Pikeienuella piscinae gen. nov., sp. nov., a novel genus in the family Rhodobacteraceae
A novel bacterium, designated strain RR4–56T, was isolated from a biofilter of a seawater recirculating aquaculture system. The 16S rRNA gene sequence analysis showed that the isolate was closely related to Halov...
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Differences in seroprevalence between epicenter and non-epicenter areas of the COVID-19 outbreak in South Korea
To compare the standardized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence of high epicenter region with non-epicenter region, serological studies were performed with a total of 3,...
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Anaerocolumna sedimenticola sp. nov., isolated from fresh water sediment
Strain CBA3638T was isolated from the Geum River sediment, Republic of Korea. The cells of strain CBA3638T were Gram-stain-positive, strictly anaerobic, rod-shaped, and 0.5–1.0 μm wide, and 4.0–4.5 μm long. Optim...
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TFEB–GDF15 axis protects against obesity and insulin resistance as a lysosomal stress response
TFEB, a key regulator of lysosomal biogenesis and autophagy, is induced not only by nutritional deficiency but also by organelle stress. Here, we find that Tfeb and its downstream genes are upregulated together w...
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Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity
NAD(P)-dependent steroid dehydrogenase-like (NSDHL), an essential enzyme in human cholesterol synthesis and a regulator of epidermal growth factor receptor (EGFR) trafficking pathways, has attracted interest a...
