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    Article

    Flavivirus NS1 protein in infected host sera enhances viral acquisition by mosquitoes

    The arbovirus life cycle involves viral transfer between a vertebrate host and an arthropod vector, and acquisition of virus from an infected mammalian host by a vector is an essential step in this process. He...

    Jianying Liu, Yang Liu, Kaixiao Nie, Senyan Du, **gjun Qiu in Nature Microbiology (2016)

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    Article

    Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

    A mutation that increases the secretion of Zika virus non-structural protein 1 (NS1) in infected hosts enhances the ability of the virus to infect its mosquito vector Aedes aegypti and might have contributed to t...

    Yang Liu, Jianying Liu, Senyan Du, Chao Shan, Kaixiao Nie, Rudian Zhang in Nature (2017)

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    Open Access

    Aedes mosquitoes acquire and transmit Zika virus by breeding in contaminated aquatic environments

    Zika virus (ZIKV) is a mosquito-borne flavivirus that predominantly circulates between humans and Aedes mosquitoes. Clinical studies have shown that Zika viruria in patients persists for an extended period, and r...

    Senyan Du, Yang Liu, Jianying Liu, Jie Zhao, Clara Champagne in Nature Communications (2019)

  4. Article

    Open Access

    A mosquito salivary protein promotes flavivirus transmission by activation of autophagy

    Transmission from an infected mosquito to a host is an essential process in the life cycle of mosquito-borne flaviviruses. Numerous studies have demonstrated that mosquito saliva facilitates viral transmission...

    Peng Sun, Kaixiao Nie, Yibin Zhu, Yang Liu, Pa Wu, Ziwen Liu in Nature Communications (2020)