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within Sebastian M. Dieter Remove this filter Oncology Remove this filter

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  1. Article

    Open Access

    The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo

    While colorectal cancer (CRC) patients with localized disease have a favorable prognosis, the five-year-survival rate in patients with distant spread is still below 15%. Hence, a detailed understanding of the ...

    Sarah Weber, Sebastian E. Koschade, Christopher M. Hoffmann… in BMC Cancer (2019)

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  2. Article

    Open Access

    Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors

    Accumulating evidence identifies non-genetic mechanisms substantially contributing to drug resistance in cancer patients. Preclinical and clinical data implicate the transcriptional co-activators YAP1 and its ...

    Sebastian M. Dieter, Domenica Lovecchio, Abhijeet Pataskar, Martina K. Zowada… in Oncogene (2022)

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