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Article

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors

Accumulating evidence identifies non-genetic mechanisms substantially contributing to drug resistance in cancer patients. Preclinical and clinical data implicate the transcriptional co-activators YAP1 and its ...

Sebastian M. Dieter, Domenica Lovecchio, Abhijeet Pataskar, Martina K. Zowada… in Oncogene (2022)