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Photochemical Internalization as a New Strategy to Enhance Efficacy of Antimicrobial Agents Against Intracellular Infections

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  1. Article

    Open Access

    A Niclosamide-releasing hot-melt extruded catheter prevents Staphylococcus aureus experimental biomaterial-associated infection

    Biomaterial-associated infections are a major healthcare challenge as they are responsible for high disease burden in critically ill patients. In this study, we have developed drug-eluting antibacterial cathet...

    Jesus Augusto Vazquez-Rodriguez, Bahaa Shaqour, Clara Guarch-Pérez in Scientific Reports (2022)

  2. Chapter

    Biomaterial-Associated Infection: Pathogenesis and Prevention

    The use of medical devices, such as urinary stents, catheters, artificial heart valves, prosthetic joints and other implants, collectively often referred to as “biomaterials” has increased dramatically over th...

    Martijn Riool, Sebastian A. J. Zaat in Urinary Stents (2022)

  3. Article

    Open Access

    Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods

    Microtiter plate methods are commonly used for biofilm assessment. However, results obtained with these methods have often been difficult to reproduce. Hence, it is important to obtain a better understanding o...

    Jontana Allkja, Frits van Charante, Juliana Aizawa, Inés Reigada in Scientific Reports (2021)

  4. Article

    Open Access

    A zebrafish high throughput screening system used for Staphylococcus epidermidisinfection marker discovery

    Staphylococcus epidermidis bacteria are a major cause of biomaterial-associated infections in modern medicine. Yet there is little known about the host responses against this normally innocent bacterium in the co...

    Wouter J Veneman, Oliver W Stockhammer, Leonie de Boer, Sebastian A J Zaat in BMC Genomics (2013)

  5. Article

    Isolation and Characterization of Promoter Regions from Streptococcus gordonii CH1

    We aimed to identify transcription signal sequences from Streptococcus gordonii strain CH1 by random chromosomal cloning. Five genomic fragments from a Sau3A digest, which constitutively activated transcription ...

    Aldwin J.M. Vriesema, Jacob Dankert, Sebastian A.J. Zaat in Current Microbiology (1999)