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Article
Designing serious games to engage children with energy saving in the home: potential learning outcomes and design considerations
The children of today will inherit a more complex domestic energy landscape than their parents. While children consume energy themselves and can meaningfully participate in energy saving, they are neglected by...
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Article
Open AccessData collection systems for active safety surveillance of vaccines during pregnancy in low- and middle-income countries: develo** and piloting an assessment tool (VPASS)
There is an urgent need for active safety surveillance to monitor vaccine exposure during pregnancy in low- and middle-income countries (LMICs). Existing maternal, newborn, and child health (MNCH) data collect...
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Article
Open AccessPatient understanding and experience of non-invasive imaging diagnostic techniques and the liver patient pathway
Clinical and patient-reported outcomes are positively affected when efforts to increase patient understanding of underlying diseases and foster patient participation are part of care pathways. The prevalence o...
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Article
Locating Hot Plasma in Small Flares using Spectroscopic Overlappogram Data from the Hinode EUV Imaging Spectrometer
One of the key processes associated with the “standard” flare model is chromospheric evaporation, a process during which plasma heated to high temperatures by energy deposition at the flare footpoints is drive...
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Article
Young driver enforcement within graduated driver licensing systems: a sco** review
Young drivers have the highest crash rates when compared with other groups of drivers. One countermeasure that has successfully reduced these crash rates is graduated driver licensing. However, young drivers’ ...
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Article
Flare-related Recurring Active Region Jets: Evidence for Very Hot Plasma
We present a study of two active region jets (AR jets) that are associated with two C-class X-ray flares. The recurrent, homologous jets originated from the northern periphery of a sunspot. We confirm flare-li...
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Article
Open AccessBeam electrons as a source of Hα flare ribbons
The observations of solar flare onsets show rapid increase of hard and soft X-rays, ultra-violet emission with large Doppler blue shifts associated with plasma upflows, and Hα hydrogen emission with red shifts up...
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Article
Open AccessThe Characteristics of Solar X-Class Flares and CMEs: A Paradigm for Stellar Superflares and Eruptions?
This paper explores the characteristics of 42 solar X-class flares that were observed between February 2011 and November 2014, with data from the Solar Dynamics Observatory (SDO) and other sources. This flare lis...
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Article
A phase II trial of ZD1839 (Iressa™) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer
Purpose: The epidermal growth factor receptor (EGFR) appears relevant in the pathogenesis and progression of colorectal cancer. After completing a phase I pharmacodynamic trial of ZD1839, we undertook a dose expa...
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Article
Phase I study of Tomudex and Doxorubicin in patients with locally advanced, inoperable or metastatic cancer (IND.98)
Background: The primary objective of this Phase I study was to determine the maximum tolerated dose (MTD) and recommended phase II dose for Tomudex and doxorubicin when given in combination to patients w...
