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  1. No Access

    Article

    Plasma Stability and Plasma Metabolite Concentration–Time Profiles of Oligo(Lactic Acid)8-Paclitaxel Prodrug Loaded Polymeric Micelles

    Paclitaxel (PTX) is a frequently prescribed chemotherapy drug used to treat a wide variety of solid tumors. Oligo(lactic acid)8-PTX prodrug (o(LA)8-PTX) loaded poly(ethylene glycol)-b-poly(lactic acid) (PEG-b-PLA...

    Lauren Repp, Sarah L. Skoczen, Morteza Rasoulianboroujeni… in The AAPS Journal (2023)

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    Protocol

    Method for Analysis of Nanoparticle Effects on Cellular Chemotaxis

    Chemotaxis is the phenomenon in which cells direct their movements in the presence of certain chemicals (chemoattractants or chemorepellents). Leukocyte recruitment (via chemotaxis) is an important component o...

    Sarah L. Skoczen, Timothy M. Potter… in Characterization of Nanoparticles Intended… (2011)

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    Protocol

    In Vitro Analysis of Nanoparticle Uptake by Macrophages Using Chemiluminescence

    This chapter provides a protocol for qualitative evaluation of nanoparticle internalization by phagocytic cells such as macrophages. This protocol uses luminol chemiluminescence to detect nanoparticle uptake. ...

    Sarah L. Skoczen, Timothy M. Potter… in Characterization of Nanoparticles Intended… (2011)