46 Result(s)

Article

What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?

The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. The World Health Organization (WHO) provides a globally applicable classification scheme...

Ayoma D. Attygalle, John K. C. Chan, Sarah E. Coupland… in Journal of Hematopathology (2024)

Article

Molekulare Diagnostik des vitreoretinalen Lymphoms

Das primäre vitreoretinale Lymphom (PVRL) stellt einen Subtyp der intraokularen Lymphome bzw. der malignen Lymphome des Auges dar. Das PVRL gilt als Sonderform des primären diffusen großzelligen Lymphoms (DLBC...

PD Dr. rer. nat. Irina Bonzheim, Julia Salmerón-Villalobos… in Die Pathologie (2023)

Article

Ruthenium¹⁰⁶ plaque brachytherapy for uveal leiomyoma: a new approach to treatment?

Katharina Eibenberger, Rumana Hussain, Yamini Krishna, Sarah E. Coupland… in Eye (2023)

Chapter

Develo** Prognostic Tools for Estimating Risk of Metastatic Death and Non-Metastatic Death in Individuals with Choroidal Melanoma

Approximately 50% of all patients with choroidal melanoma develop metastatic disease after months or years of apparent good health following ocular treatment. We have developed mathematical models to estimate ...

Bertil E. Damato, Antonio Eleuteri… in Global Perspectives in Ocular Oncology (2022)

Chapter

Application of Deep Learning Models in the Evaluation of Histopathology of Uveal Melanoma

Digital pathology is being increasingly implemented in basic and translational research, as well as in routine clinical care for diagnostics and prognostication. With the latter, it is essentially an additiona...

Sarah E. Coupland, Hongrun Zhang, Hayley Jones… in Global Perspectives in Ocular Oncology (2022)

Chapter

Intraocular Lymphomas

Lymphoma is a malignant neoplasm derived from monoclonal proliferations of B- or T-lymphocytes and rarely, natural killer (NK) cells. Ophthalmic involvement is relatively rare and may involve the ocular adnexa...

Kaustubh Mulay, Santosh G. Honavar, Santosh U. Kafle… in Intraocular Tumors (2020)

Chapter

Genetics of Uveal Melanoma

Uveal melanoma is a rare, aggressive intraocular malignant tumor, leading to metastatic disease in over 50% of patients with tumors located in the ciliary body or choroid. Genetic studies have identified chrom...

Helen Kalirai, Alexander Iu. Tsygankov, Sophie Thornton… in Intraocular Tumors (2020)

Chapter

Classification of Uveal Tumors

Tumors of the same class should share a unique combination of features, which distinguishes them from all other classes. Classification, therefore, is the process of defining different tumor classes and correl...

Bertil E. Damato, Sarah E. Coupland in Clinical Ophthalmic Oncology (2019)

Chapter

Diagnostic Techniques: Other Biopsy Techniques

Alternatives to fine-needle aspiration biopsy include vitreous cutter aspiration biopsy, incisional biopsy, and excisional biopsy. Vitreous cutter aspiration biopsy is performed with a 25- or 27-gauge vitreous...

Bertil E. Damato, Armin Afshar, Sarah E. Coupland… in Clinical Ophthalmic Oncology (2019)

Chapter

Uveal Melanoma: Molecular Pathology

Research into the molecular genetics of uveal melanomas (UM) has identified several predictors of metastatic disease as well as signaling pathways and molecules that can be targeted using systemic therapies. M...

Sarah E. Coupland, Helen Kalirai, Sophie Thornton… in Clinical Ophthalmic Oncology (2019)

Chapter

Uveal Melanoma: Prognostication Methods

Almost 50% of uveal melanoma (UM) patients develop metastatic disease, despite successful ocular treatment. Metastases usually involve the liver and only rarely respond to treatment so that most patients die w...

Sarah E. Coupland, Azzam Taktak, Antonio Eleuteri… in Clinical Ophthalmic Oncology (2019)

Chapter

Uveal Lymphoproliferative Tumors

Lymphoid proliferations of the uvea can be divided into two main groups: (a) primary uveal tumors and (b) secondary intraocular manifestations of systemic lymphoma. Although the exact frequency of the latter i...

Sarah E. Coupland, Arun D. Singh in Clinical Ophthalmic Oncology (2019)

Article

Recurrent chordoma with orbital and eyelid invasion

Yamini Krishna, Saad Qureshi… in Graefe's Archive for Clinical and Experime… (2017)

Article

Adipophilin expression in primary and metastatic uveal melanoma: a pilot study

Miltiadis Fiorentzis, Helen Kalirai… in Graefe's Archive for Clinical and Experime… (2017)

Chapter

Animal Models of Ocular Tumors

Ocular oncology includes many rare malignancies, for which clinical trials are often logistically very difficult to undertake. Consequently, in order to test new drugs for ocular tumors, cell lines are often r...

Martine J. Jager, **feng Cao, Hua Yang… in Animal Models of Ophthalmic Diseases (2016)