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Article
Open AccessCircular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival
Hypertrophic cardiomyopathy (HCM) constitutes the most common genetic cardiac disorder. However, current pharmacotherapeutics are mainly symptomatic and only partially address underlying molecular mechanisms. ...
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Protocol
Encapsulating In Vitro Transcribed circRNA into Lipid Nanoparticles Via Microfluidic Mixing
This chapter serves as a guide for researchers embarking on circular RNA-based translational studies. It provides a foundation for the successful encapsulation of circular RNA into lipid nanoparticles (LNPs) a...
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Chapter
Gene Therapy and Cardiovascular Diseases
Cardiovascular diseases (CVDs) are the leading causes of death globally and urgently require new novel therapeutic strategies. Gene therapy is the application of gene modulation technology to treat abnormal ge...
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Article
Open AccessNeonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration
Myocardial injury often leads to heart failure due to the loss and insufficient regeneration of resident cardiomyocytes. The low regenerative potential of the mammalian heart is one of the main drivers of hear...
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Chapter
The Auschwitz Women’s Camp: An Overview and Reconsideration
While many know of Auschwitz and its genocidal sub-camp Birkenau, few are familiar with the women’s section. This chapter offers an overview of the women’s camp in Auschwitz-Birkenau: a place, its denizens—per...
