-
Article
Open AccessStudying missingness in spinal cord injury data: challenges and impact of data imputation
In the last decades, medical research fields studying rare conditions such as spinal cord injury (SCI) have made extensive efforts to collect large-scale data. However, most analysis methods rely on complete d...
-
Article
Open AccessAuthor Correction: Intermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements
-
Chapter and Conference Paper
Modelling Direct and Indirect Effects of Radiation: Experimental, Clinical and Environmental Implications
Radiotherapy is a commonly used treatment for cancer and is usually given in varying doses. Mathematical modelling of radiation effects traditionally means the modelling or estimation of cell-kill due to its d...
-
Article
Open AccessIntermittent radiotherapy as alternative treatment for recurrent high grade glioma: a modeling study based on longitudinal tumor measurements
Recurrent high grade glioma patients face a poor prognosis for which no curative treatment option currently exists. In contrast to prescribing high dose hypofractionated stereotactic radiotherapy (HFSRT, ...
-
Article
Open Access3D tumour spheroids for the prediction of the effects of radiation and hyperthermia treatments
For multimodality therapies such as the combination of hyperthermia and radiation, quantification of biological effects is key for dose prescription and response prediction. Tumour spheroids have a microenviro...
-
Article
Open AccessA cellular automaton model for spheroid response to radiation and hyperthermia treatments
Thermo-radiosensitisation is a promising approach for treatment of radio-resistant tumours such as those containing hypoxic subregions. Response prediction and treatment planning should account for tumour resp...
