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Article
Open AccessExercise as a protective mechanism against the negative effects of oxidative stress in first-episode psychosis: a biomarker-led study
First-episode psychosis (FEP) is a psychiatric disorder, characterised by positive and negative symptoms, usually emerging during adolescence and early adulthood. FEP represents an early intervention opportuni...
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Reference Work Entry In depth
Oxidative Stress
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Reference Work Entry In depth
Steroids
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Reference Work Entry In depth
Antioxidant
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Reference Work Entry In depth
Nitric Oxide Synthase (NOS)
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Article
Open AccessInflammation Mediates Body Weight and Ageing Effects on Psychomotor Slowing
Inflammation (immune system activation) affects neuronal function and may have consequences for the efficiency and speed of functional brain processes. Indeed, unusually slow psychomotor speed, a measure predi...
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Living Reference Work Entry In depth
Antioxidant
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Living Reference Work Entry In depth
Steroids
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Living Reference Work Entry In depth
Nitric Oxide Synthase (NOS)
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Living Reference Work Entry In depth
Oxidative Stress
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Article
Three months of moderate-intensity exercise reduced plasma 3-nitrotyrosine in rheumatoid arthritis patients
Rheumatoid arthritis (RA) patients display high levels of oxidative stress. Transient exercise-induced increases in oxidative stress are thought to be adaptive in healthy populations. This study investigated t...
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Article
Open AccessPlasma irisin levels predict telomere length in healthy adults
The ageing process is strongly influenced by nutrient balance, such that modest calorie restriction (CR) extends lifespan in mammals. Irisin, a newly described hormone released from skeletal muscles after exer...
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Article
Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults
Ageing is associated with a decline in immune competence termed immunosenescence. In the elderly, this process results in an accumulation of differentiated ‘effector’ phenotype memory T cells, predominantly dr...
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Article
The interactions of oxidative stress and inflammation with vascular dysfunction in ageing: the vascular health triad
Oxidative stress and inflammation are increased with advancing age. Evidence suggests that oxidative stress and inflammation both lead to impaired vascular function. There is also evidence to suggest that infl...
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Article
Plasma Amino Acid Levels in Children with Autism and Their Families
Plasma amino acid levels were measured in autistic and Asperger syndrome patients, their siblings, and parents. The results were compared with values from age-matched controls. Patients with autism or Asperger...