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  1. Article

    Open Access

    Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover

    The transcription factor GATA3 is a favorable prognostic indicator in estrogen receptor-α (ERα)-positive breast tumors in which it participates with ERα and FOXA1 in a complex transcriptional regulatory progra...

    Aleksandra B Adomas, Sara A Grimm, Christine Malone, Motoki Takaku… in BMC Cancer (2014)

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    Article

    An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

    Dmitry Gordenin, Gad Getz and colleagues report an analysis of mutation patterns in cancer genomes and find evidence of mutagenesis induced by APOBEC cytidine deaminase enzymes. They find an APOBEC mutagenesis...

    Steven A Roberts, Michael S Lawrence, Leszek J Klimczak, Sara A Grimm… in Nature Genetics (2013)