![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Purification of 99Mo and 99mTc from radioactive traces of Nb, Zr, and Y impurities: method applicable in the purification of the spent 100/99Mo–99mTc generator
The aim of this work was to develop a method for purification of the spent 100/99Mo–99mTc generator free from non-isotopic impurities like Nb, Y, Zr and recovery of 99mTc using a Sephadex column and MEK solvent e...
-
Article
Production and radiochemical separation of a potential immuno-PET imaging agent 89Zr from proton irradiated natY target
Zirconium-89 (89Zr) is an interesting immuno-PET imaging agent due to its favorable physical characteristics of 78.4 h half-life and a relatively low positron energy of 0.9 MeV. Radiochemical separation of 89Zr f...
-
Article
Preparation of 99Mo/99mTc generator based on cross-linked chitosan polymer using low-specific activity (n,γ)99Mo
The cross-linked chitosan polymer (CCM) is an emerging adsorbent matrix. The CCM matrix has very high adsorption for Mo and thus can be utilized to prepare 99Mo/99mTc generator using low-specific activity (n, γ)
-
Article
Separation of Mo from Nb, Zr and Y: applicability in the purification of the recovered enriched 100Mo used in the direct production of 99mTc in cyclotrons
The direct production of 99mTc in cyclotrons by the proton irradiation of highly enriched 100Mo requires recovery of the costly enriched 100Mo from the irradiated target to keep the cost of 99mTc within the affor...
-
Article
Production and separation of 99mTc from cyclotron irradiated 100/naturalMo targets: a new automated module for separation of 99mTc from molybdenum targets
The direct production of 99mTc through (p, 2n) reaction on natural molybdenum target and enriched 100Mo target was investigated. Separation of technetium radionuclide from the irradiated 100Mo target by a new met...
-
Article
Fabrication of surfactant-free quercetin-loaded PLGA nanoparticles: evaluation of hepatoprotective efficacy by nuclear scintigraphy
The purpose of this study was to develop surfactant-free quercetin-loaded PLGA nanoparticles (Qr-NPs) and investigate the hepatoprotective efficacy of the product non-invasively by nuclear scintigraphy. The na...
-
Article
Synthesis, characterization, biodistribution and scintigraphy of 99mTc-paclitaxel: a potential tracer of paclitaxel
99mTc-paclitaxel was synthesized by using sodium borohydride as a reducing agent. Greater than 95 % labelling efficiency was achieved. Radiochemical purity of the synthesized 99mTc-paclit...
-
Article
An easy and effective method for radiolabelling of solid lipid nanoparticles
Nanoparticle biodistribution study is of great importance in bringing nanomedicine to patients. In this article, solid lipid nanoparticle (SLN) with dimension less than 100 nm was successfully radiolabelled with
-
Article
Pharmaceutical grade sodium [99mTc] pertechnetate from low specific activity 99Mo using an automated 99Mo/99mTc-TCM-autosolex generator
Performance study of a computer controlled automated closed cyclic module for the separation and recovery of 99mTc from low specific activity (n, γ) 99Mo using methyl ethyl ketone (MEK) solvent extraction techniq...
-
Article
Synthesis, radiolabelling and biodistribution of HYNIC-Tyr3 octreotide: a somatostatin receptor positive tumour imaging agent
In vivo imaging of tumours using radiolabelled somatostatin (SST) analogues has become an accepted clinical tool in oncology. HYNIC-Tyr3 octreotide and Tyr3 octreotide were synthesized by FMOC solid-phase peptide...
-
Article
Ethylene dicysteine (EC) and ethyl cysteinate dimer (ECD) complexes of Ga(III) and In(III)
Ethylene dicysteine (EC) and ethyl cysteinate dimer (ECD) complexes of67Ga and111In were prepared and the complexation yield and radiochemical purity estimated by paper chromatography, paper electrophoresis and s...