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Article
Open AccessManufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine
Centrin1 gene deleted Leishmania donovani parasite (LdCen1−/−) was developed and extensively tested experimentally as an intracellular stage-specific attenuated and immunoprotective live parasite vaccine candidat...
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Article
Open AccessAn Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial
Here we conducted a multicenter open-label, randomized phase 2 and 3 study to assess the safety and immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron-specific (BA.1/B.1.1...
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Article
Open AccessDesymmetric homologating annulation to access chiral pentafulvenes and their application in bioimaging
The architectural design of polycyclic/multisubstituted pentafulvenes has demonstrated great potential for the development of electrochromic materials and biologically active motifs. Unfortunately, the enantio...
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Article
Open AccessGrain iron and zinc content is independent of anthocyanin accumulation in pigmented rice genotypes of Northeast region of India
The traditional rice genotypes of Assam are considered to have biological value due to the presence of several bioactive compounds like flavonoids, polyphenols, and anthocyanins, which have antioxidant, anti-c...
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Article
Open AccessCholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation
The involvement of the autonomic nervous system in the regulation of inflammation is an emerging concept with significant potential for clinical applications. Recent studies demonstrate that stimulating the va...
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Article
Open AccessInvestigating the phenology and interactions of competitive plant species co-occurring with invasive Lantana camara in Indian Himalayan Region
Invasive plant species are considered one of the significant drivers of habitat loss, leading to biodiversity loss. They have also been observed to alter the local ecology, resulting in a decline of native flo...
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Article
Open AccessProduction of leishmanin skin test antigen from Leishmania donovani for future reintroduction in the field
The leishmanin skin test was used for almost a century to detect exposure and immunity to Leishmania, the causative agent of leishmaniasis, a major neglected tropical disease. Due to a lack of antigen used for th...
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Article
Publisher Correction to: Development of a robust structural health monitoring system: a wireless sensor network approach
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Article
Facial expression recognition in videos using hybrid CNN & ConvLSTM
The three-dimensional convolutional neural network (3D-CNN) and long short-term memory (LSTM) have consistently outperformed many approaches in video-based facial expression recognition (VFER). The image is un...
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Article
Three-dimensional DenseNet self-attention neural network for automatic detection of student’s engagement
Today, due to the widespread outbreak of the deadly coronavirus, popularly known as COVID-19, the traditional classroom education has been shifted to computer-based learning. Students of various cognitive and ...
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Article
Open AccessTherapeutic potential of venom peptides: insights in the nanoparticle-mediated venom formulations
Venoms are the secretions produced by animals, generally for the purpose of self-defense or catching a prey. Biochemically venoms are mainly composed of proteins, lipids, carbohydrates, ions, etc., and classif...
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Article
Open AccessTranslational development of a tumor junction opening technology
Our goal is to overcome treatment resistance in ovarian cancer patients which occurs in most cases after an initial positive response to chemotherapy. A central resistance mechanism is the maintenance of desmo...
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Article
Open AccessValidation of expert system enhanced deep learning algorithm for automated screening for COVID-Pneumonia on chest X-rays
SARS-CoV2 pandemic exposed the limitations of artificial intelligence based medical imaging systems. Earlier in the pandemic, the absence of sufficient training data prevented effective deep learning (DL) solu...
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Article
Open AccessAutomatic question-answer pairs generation and question similarity mechanism in question answering system
With the swift growth of the information over the past few years, taking full benefit is increasingly essential. Question Answering System is one of the promising methods to access this much information. The Q...
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Article
Open AccessPreclinical validation of a live attenuated dermotropic Leishmania vaccine against vector transmitted fatal visceral leishmaniasis
Visceral Leishmaniasis (VL), a potentially fatal disease is caused by Leishmania donovani parasites with no vaccine available. Here we produced a dermotropic live attenuated centrin gene deleted Leishmania major ...
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Article
Open AccessSemi-supervised deep learning based named entity recognition model to parse education section of resumes
A job seeker’s resume contains several sections, including educational qualifications. Educational qualifications capture the knowledge and skills relevant to the job. Machine processing of the education secti...
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Article
Open AccessOxidative stress-mediated genotoxic effect of zinc oxide nanoparticles on Deinococcus radiodurans
Extensive use of nanomaterials in consumer products has invoked the concerns about interactions of nanoparticles with living organisms (including microorganisms). Zinc oxide nanoparticles (ZnO NPs) are well kn...
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Article
Open AccessReal-time high-resolution video stabilization using high-frame-rate jitter sensing
In this study, the novel approach of real-time video stabilization system using a high-frame-rate (HFR) jitter sensing device is demonstrated to realize the computationally efficient technique of digital video...
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Article
Open AccessExotic magnetic behaviour and evidence of cluster glass and Griffiths like phase in Heusler alloys Fe2-xMnxCrAl (0 ≤ x ≤ 1)
We present a detailed study of structural, magnetic and thermodynamic properties of a series of Heusler alloys Fe2-xMnxCrAl (x = 0, 0.25, 0.5, 0.75 and 1). Structural investigation of this series is carried out u...
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Chapter and Conference Paper
Real-Time Vehicle Detection in Aerial Images Using Skip-Connected Convolution Network with Region Proposal Networks
Detection of objects in aerial images has gained significant attention in recent years, due to its extensive needs in civilian and military reconnaissance and surveillance applications. With the advent of Unma...