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  1. Article

    Open Access

    Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine

    Centrin1 gene deleted Leishmania donovani parasite (LdCen1−/−) was developed and extensively tested experimentally as an intracellular stage-specific attenuated and immunoprotective live parasite vaccine candidat...

    Kumar Avishek, Mirza A. Beg, Kavita Vats, Avinash Kumar Singh in Scientific Reports (2024)

  2. Article

    Open Access

    Desymmetric homologating annulation to access chiral pentafulvenes and their application in bioimaging

    The architectural design of polycyclic/multisubstituted pentafulvenes has demonstrated great potential for the development of electrochromic materials and biologically active motifs. Unfortunately, the enantio...

    Sanjay Singh, Ravi Saini, Akshay Joshi, Neetu Singh, Ravi P. Singh in Nature Communications (2024)

  3. Article

    Open Access

    Grain iron and zinc content is independent of anthocyanin accumulation in pigmented rice genotypes of Northeast region of India

    The traditional rice genotypes of Assam are considered to have biological value due to the presence of several bioactive compounds like flavonoids, polyphenols, and anthocyanins, which have antioxidant, anti-c...

    Smrita Gogoi, Sanjay Singh, B. P. Mallikarjuna Swamy, Priyanka Das in Scientific Reports (2024)

  4. Article

    Open Access

    Investigating the phenology and interactions of competitive plant species co-occurring with invasive Lantana camara in Indian Himalayan Region

    Invasive plant species are considered one of the significant drivers of habitat loss, leading to biodiversity loss. They have also been observed to alter the local ecology, resulting in a decline of native flo...

    Abhishek Kumar, Sanjay Singh, Dinesh Kumar, Ram Kumar Singh in Scientific Reports (2024)

  5. Article

    Open Access

    Production of leishmanin skin test antigen from Leishmania donovani for future reintroduction in the field

    The leishmanin skin test was used for almost a century to detect exposure and immunity to Leishmania, the causative agent of leishmaniasis, a major neglected tropical disease. Due to a lack of antigen used for th...

    Ranadhir Dey, Jalal Alshaweesh, Kamaleshwar P. Singh in Nature Communications (2023)

  6. Article

    Open Access

    Translational development of a tumor junction opening technology

    Our goal is to overcome treatment resistance in ovarian cancer patients which occurs in most cases after an initial positive response to chemotherapy. A central resistance mechanism is the maintenance of desmo...

    Jiho Kim, Chang Li, Hongjie Wang, Swarnendu Kaviraj, Sanjay Singh in Scientific Reports (2022)

  7. Article

    Open Access

    Validation of expert system enhanced deep learning algorithm for automated screening for COVID-Pneumonia on chest X-rays

    SARS-CoV2 pandemic exposed the limitations of artificial intelligence based medical imaging systems. Earlier in the pandemic, the absence of sufficient training data prevented effective deep learning (DL) solu...

    Prashant Sadashiv Gidde, Shyam Sunder Prasad, Ajay Pratap Singh in Scientific Reports (2021)

  8. Article

    Open Access

    Exotic magnetic behaviour and evidence of cluster glass and Griffiths like phase in Heusler alloys Fe2-xMnxCrAl (0 ≤ x ≤ 1)

    We present a detailed study of structural, magnetic and thermodynamic properties of a series of Heusler alloys Fe2-xMnxCrAl (x = 0, 0.25, 0.5, 0.75 and 1). Structural investigation of this series is carried out u...

    Kavita Yadav, Mohit K. Sharma, Sanjay Singh, K. Mukherjee in Scientific Reports (2019)

  9. Article

    Open Access

    Harnessing genetic potential of wheat germplasm banks through impact-oriented-prebreeding for future food and nutritional security

    The value of exotic wheat genetic resources for accelerating grain yield gains is largely unproven and unrealized. We used next-generation sequencing, together with multi-environment phenoty**, to study the ...

    Sukhwinder Singh, Prashant Vikram, Deepmala Sehgal, Juan Burgueño in Scientific Reports (2018)

  10. Article

    Open Access

    Robust Bain distortion in the premartensite phase of a platinum-substituted Ni2MnGa magnetic shape memory alloy

    The premartensite phase of shape memory and magnetic shape memory alloys (MSMAs) is believed to be a precursor state of the martensite phase with preserved austenite phase symmetry. The thermodynamic stability...

    Sanjay Singh, B. Dutta, S. W. D’Souza, M. G. Zavareh, P. Devi in Nature Communications (2017)

  11. Article

    Open Access

    Multiple Dirac cones at the surface of the topological metal LaBi

    The rare-earth monopnictide LaBi exhibits exotic magneto-transport properties, including an extremely large and anisotropic magnetoresistance. Experimental evidence for topological surface states is still miss...

    Jayita Nayak, Shu-Chun Wu, Nitesh Kumar, Chandra Shekhar in Nature Communications (2017)

  12. Article

    Open Access

    Room-temperature tetragonal non-collinear Heusler antiferromagnet Pt2MnGa

    Antiferromagnetic spintronics is a rapidly growing field, which actively introduces new principles of magnetic storage. Despite that, most applications have been suggested for collinear antiferromagnets. In th...

    Sanjay Singh, S. W. D’Souza, J. Nayak, E. Suard, L. Chapon in Nature Communications (2016)