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Open AccessDevelo** centrifugal force real-time digital PCR for detecting extremely low DNA concentration
Digital PCR (dPCR) is a technique for absolute quantification of nucleic acid molecules. To develop a dPCR technique that enables more accurate nucleic acid detection and quantification, we established a novel...
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Article
Open AccessCharacterization of a novel yeast species Metschnikowia persimmonesis KCTC 12991BP (KIOM G15050 type strain) isolated from a medicinal plant, Korean persimmon calyx (Diospyros kaki Thumb)
The yeast strain Metschnikowia persimmonesis Kang and Choi et al., sp. nov. [type strain KIOM_G15050 = Korean Collection for Type Cultures (KCTC) 12991BP] was isolated from the stalk of native persimmon cultivars...
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Article
Lactobacillus plantarum HAC01 regulates gut microbiota and adipose tissue accumulation in a diet-induced obesity murine model
The functional features of Lactobacillus plantarum HAC01 (HAC01), isolated from fermented Korean kimchi, were studied with regard to the fat mass, immunometabolic biomarkers and dysbiosis in a diet-induced obesit...
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Article
Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population
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Article
Profiling of the bacteria responsible for pyogenic liver abscess by 16S rRNA gene pyrosequencing
Pyogenic liver abscess (PLA) is a severe disease with considerable mortality and is often polymicrobial. Understanding the pathogens that cause PLA is the basis for PLA treatment. Here, we profiled the bacteri...
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Article
Open AccessAnalyses of pig genomes provide insight into porcine demography and evolution
For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and...
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Article
UbC gene allele frequency in Korean population and novel UbC mosaic repeat unit formation
The genomic structural organization of human UbC CDS repeat units could be representative of concerted evolution. The structure of the UbC gene and its repeat unit number frequency at scales of different human et...
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Article
Novel mechanism of conjoined gene formation in the human genome
Recently, conjoined genes (CGs) have emerged as important genetic factors necessary for understanding the human genome. However, their formation mechanism and precise structures have remained mysterious. Based...
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EST Analysis Predicts Putatively Causative Genes Underlying the Pharmaceutical Application of Glycyrrhiza uralensis Fisch
Glycyrrhiza uralensis Fisch is an important medicinal plant used not only as a natural sweetener but also for a variety of pharmaceutical applications. Even though there have been previous reports of genes putati...
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Article
Major chimpanzee-specific structural changes in sperm development-associated genes
A comprehensive analysis of transcriptional structures of chimpanzee sperm development-associated genes is of significant interest for deeply understanding sperm development and male reproductive process. In t...
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Article
Open AccessIdentification of a Novel Garlic Cellulase Gene
Genes encoding cellulase enzymes have been investigated in various plants due to the importance of cellulase enzymes in industrial applications, especially in the conversion of biomass into biofuels. Although ...
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Article
Comparative analysis of expressed sequence tags from the white-rot fungi (Phanerochaete chrysosporium)
Comprehensive analysis of the transcriptome of the P. chrysosporium is a useful approach to improve our understanding of its special and unique enzyme system and fungal evolution in molecular and industrial aspec...
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Article
Open AccessGarlicESTdb: an online database and mining tool for garlic EST sequences
Allium sativum., commonly known as garlic, is a species in the onion genus (Allium), which is a large and diverse one containing over 1,250 species. Its close relatives include chives, onion, leek and shallot. Ga...
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Comparative analysis of chimpanzee and human Y chromosomes unveils complex evolutionary pathway
The mammalian Y chromosome has unique characteristics compared with the autosomes or X chromosomes. Here we report the finished sequence of the chimpanzee Y chromosome (PTRY), including 271 kb of the Y-specifi...
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Article
Identification of novel allele on the locus 47z (DXYS5) in the Korean population
Two homogenous sequences of 47z (DXYS5) are located on the X (DXYS5X) and Y (DXYS5Y) chromosomes, and these are known to be useful polymorphic markers for tracing male-specific gene flow such as the migration rou...
