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12,102 Result(s)
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Article
Assessment of the predictive capabilities of various turbulence models for the simulation of rotating stall in the centrifugal pump impeller
The rotating stall generated by the centrifugal pump impeller reduces efficiency and causes severe flow fluctuations and noise due to surging. In the present work, the six-bladed impeller in the centrifugal pu...
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Publisher Correction: Short-term inhalation exposure to cigarette smoke induces oxidative stress and inflammation in lungs without systemic oxidative stress in mice
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Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers
The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gyeongsang Province of South Korea. K. adamsi has been classified under the Endangered Wildli...
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3D Bioprinting Strategies for Articular Cartilage Tissue Engineering
Articular cartilage is the avascular and aneural tissue which is the primary connective tissue covering the surface of articulating bone. Traumatic damage or degenerative diseases can cause articular cartilage...
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Thermoelectric Transport Properties of Co0.5Fe0.5Se2, Co0.5Fe0.5Te2, and Their Solid-Solution Compositions
Transition-metal chalcogenides with tunable electronic transport properties and unique crystal structures have attracted much attention as potential thermoelectric materials. In this study, the electrical, the...
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Prediction of spring steel wire rod hardness based on wire rod rolling process data: a case study
This study aims to predict the hardness of steel wire rods produced in the actual process by using statistical analysis and machine learning algorithms. The prediction model is built through five steps: operat...
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Effect of mesophase formation from quinoline insoluble-containing coal tar pitch on physical properties of carbon blocks
In the present study, a coal-based pitch containing 12.1% quinoline insoluble (QI) underwent isothermal heat treatment, and changes in the mesophase microstructure were analyzed for the heat treatment duration...
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Genotoxicity and safety pharmacology of the rVSVInd(GML)-mspSGtc vaccine against SARS-CoV-2 in Sprague–Dawley rats and Beagle dogs
The emergence of coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a pandemic, prompting rapid vaccine development. Although vaccines are effective, t...
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Intranasal delivery of siRNA targeting NR2B attenuates cancer-associated neuropathic pain
This study aimed to reduce cancer-associated pain by blocking pain signals through the intranasal administration of siRNA targeting the NMDA subunit NR2B (siNR2B).
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Open AccessNegative regulation of HDAC3 transcription by histone acetyltransferase TIP60 in colon cancer
Colon cancer is the third most common cancer globally. The expression of histone deacetylase 3 (HDAC3) is upregulated, whereas the expression of tat interactive protein, 60 kDa (TIP60) is downregulated in colon c...
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Development of Cell Culture Platforms for Study of Trabecular Meshwork Cells and Glaucoma Development
Various cell culture platforms that could display native environmental cue-mimicking stimuli were developed, and effects of environmental cues on cell behaviors were studied with the cell culture platforms. Li...
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Blocking Fas signaling in adipose tissue ameliorates obesity-associated inflammation, insulin resistance, and hepatosteatosis
Adipose tissue inflammation is a crucial early stage of obesity-related metabolic dysfunction and insulin resistance. Adipocytes, and infiltrating immune cells in the adipose tissue, play significant roles in ...
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Effect of fiber orientation on spinning dynamics for liquid crystalline polymer solutions using mesoscopic theory
Liquid crystalline polymer (LCP) solutions undergo uniaxial elongation in fiber spinning, yielding highly oriented fibril-structured fibers with enhanced orientation and mechanical properties. This study explo...
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Open AccessProton-pum** photoreceptor controls expression of ABC transporter by regulating transcription factor through light
Light is a significant factor for living organisms with photosystems, like microbial rhodopsin—a retinal protein that functions as an ion pump, channel, and sensory transduction. Gloeobacter violaceus PCC7421, ha...
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Open AccessPrediction model for cardiovascular disease in patients with diabetes using machine learning derived and validated in two independent Korean cohorts
This study aimed to develop and validate a machine learning (ML) model tailored to the Korean population with type 2 diabetes mellitus (T2DM) to provide a superior method for predicting the development of card...
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Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer
Metastasis occurs frequently after resection of pancreatic cancer (PaC). In this study, we hypothesized that multi-parametric analysis of pre-metastatic liver biopsies would classify patients according to thei...
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Open AccessLimited impact of bacterial virulence on early mortality risk factors in Acinetobacter baumannii bacteremia observed in a Galleria mellonella model
Acinetobacter baumannii (AB) has emerged as a major pathogen in vulnerable and severely ill patients. It remains unclear whether early mortality (EM) due to AB bacteremia is because of worse clinical characterist...
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Open AccessSolar-driven highly selective conversion of glycerol to dihydroxyacetone using surface atom engineered BiVO4 photoanodes
Dihydroxyacetone is the most desired product in glycerol oxidation reaction because of its highest added value and large market demand among all possible oxidation products. However, selectively oxidative seco...
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Microscopic Study on the Blister Formation Mechanism in Electrogalvanized Steel
The blister formation mechanism in electrogalvanized steel was studied by analyzing the blister’s internal structure. Electrochemical hydrogen charging was employed to absorb hydrogen into the steel plate and ...
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Open AccessSequence-specific dynamic DNA bending explains mitochondrial TFAM’s dual role in DNA packaging and transcription initiation
Mitochondrial transcription factor A (TFAM) employs DNA bending to package mitochondrial DNA (mtDNA) into nucleoids and recruit mitochondrial RNA polymerase (POLRMT) at specific promoter sites, light strand pr...