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Article
A species-level timeline of mammal evolution integrating phylogenomic data
High-throughput sequencing projects generate genome-scale sequence data for species-level phylogenies1–3. However, state-of-the-art Bayesian methods for inferring timetrees are computationally limited to small da...
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Article
Dire wolves were the last of an ancient New World canid lineage
Dire wolves are considered to be one of the most common and widespread large carnivores in Pleistocene America1, yet relatively little is known about their evolution or extinction. Here, to reconstruct the evolut...
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Chapter
Bayesian Phylogenomic Dating
The development of divergence-time estimation methods has been an active area of research since the early 1960s, when the molecular clock was first postulated by Zuckerkandl and Pauling. Thanks to technologica...
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Article
Open AccessThe bile salt glycocholate induces global changes in gene and protein expression and activates virulence in enterotoxigenic Escherichia coli
Pathogenic bacteria use specific host factors to modulate virulence and stress responses during infection. We found previously that the host factor bile and the bile component glyco-conjugated cholate (NaGCH, ...