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  1. Article

    Open Access

    The substrate specificity switch FlhB assembles onto the export gate to regulate type three secretion

    Protein secretion through type-three secretion systems (T3SS) is critical for motility and virulence of many bacteria. Proteins are transported through an export gate containing three proteins (FliPQR in flage...

    Lucas Kuhlen, Steven Johnson, Andreas Zeitler, Sandra Bäurle in Nature Communications (2020)

  2. Article

    Open Access

    Revealing the mechanisms of membrane protein export by virulence-associated bacterial secretion systems

    Many bacteria export effector proteins fulfilling their function in membranes of a eukaryotic host. These effector membrane proteins appear to contain signals for two incompatible bacterial secretion pathways ...

    Lea Krampen, Silke Malmsheimer, Iwan Grin, Thomas Trunk in Nature Communications (2018)

  3. Article

    Open Access

    Isolation and characterization of the E. coli membrane protein production strain Mutant56(DE3)

    Membrane protein production is usually toxic to E. coli. However, using genetic screens strains can be isolated in which the toxicity of membrane protein production is reduced, thereby improving production yields...

    Thomas Baumgarten, Susan Schlegel, Samuel Wagner, Mirjam Löw in Scientific Reports (2017)

  4. Article

    Open Access

    Enhancing quantum sensing sensitivity by a quantum memory

    In quantum sensing, precision is typically limited by the maximum time interval over which phase can be accumulated. Memories have been used to enhance this time interval beyond the coherence lifetime and thus...

    Sebastian Zaiser, Torsten Rendler, Ingmar Jakobi, Thomas Wolf in Nature Communications (2016)