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  1. Article

    Open Access

    CpG island-mediated global gene regulatory modes in mouse embryonic stem cells

    Both transcriptional and epigenetic regulations are fundamental for the control of eukaryotic gene expression. Here we perform a compendium analysis of >200 large sequencing data sets to elucidate the regulato...

    Samuel Beck, Bum-Kyu Lee, Catherine Rhee, Jawon Song in Nature Communications (2014)

  2. Article

    Open Access

    Super-enhancer-guided map** of regulatory networks controlling mouse trophoblast stem cells

    Trophectoderm (TE) lineage development is pivotal for proper implantation, placentation, and healthy pregnancy. However, only a few TE-specific transcription factors (TFs) have been systematically characterize...

    Bum-Kyu Lee, Yu ** Jang, Mijeong Kim, Lucy LeBlanc in Nature Communications (2019)

  3. Article

    Open Access

    A text-mining based analysis of 100,000 tumours affecting dogs and cats in the United Kingdom

    Cancer is a major reason for veterinary consultation, especially in companion animals. Cancer surveillance plays a key role in prevention but opportunities for such surveillance in companion animals are limite...

    José Rodríguez, David R. Killick, Lorenzo Ressel in Scientific Data (2021)