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Article
Open AccessCpG island-mediated global gene regulatory modes in mouse embryonic stem cells
Both transcriptional and epigenetic regulations are fundamental for the control of eukaryotic gene expression. Here we perform a compendium analysis of >200 large sequencing data sets to elucidate the regulato...
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Article
Open AccessSuper-enhancer-guided map** of regulatory networks controlling mouse trophoblast stem cells
Trophectoderm (TE) lineage development is pivotal for proper implantation, placentation, and healthy pregnancy. However, only a few TE-specific transcription factors (TFs) have been systematically characterize...
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Article
Open AccessA text-mining based analysis of 100,000 tumours affecting dogs and cats in the United Kingdom
Cancer is a major reason for veterinary consultation, especially in companion animals. Cancer surveillance plays a key role in prevention but opportunities for such surveillance in companion animals are limite...