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  1. Article

    Open Access

    Actigraphy-based sleep and activity measurements in intensive care unit patients randomized to ramelteon or placebo for delirium prevention

    Patients in the ICU often sleep poorly for various reasons, which may predispose to delirium. We previously conducted a clinical trial in which we tested the efficacy of ramelteon, a melatonin-receptor agonist...

    Stuti J. Jaiswal, Samantha R. Spierling Bagsic, Emerson Takata… in Scientific Reports (2023)

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  2. No Access

    Article

    Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders

    Alcohol use disorder (AUD) and anxiety disorders are frequently comorbid and share mechanisms that could be therapeutic targets. To facilitate mechanistic studies, we adapted an inhibitory avoidance-based “2-h...

    Michael Q. Steinman, Dean Kirson, Sarah A. Wolfe, Sophia Khom… in Molecular Psychiatry (2021)