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Sabela Da Silva-Álvarez
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Article
Open AccessAuthor Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Senotherapy of Cancer
Cellular senescence is a stress and repair response that protects us from cancer and contributes to tissue homeostasis by inducing a stable cell cycle arrest and imposing a secretory phenotype. Senescent cells...
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Article
Open AccessIdentification and characterization of Cardiac Glycosides as senolytic compounds
Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the causal involvement of senescence in aging and offer therapeutic interventions. Here we report the identification of Car...
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Article
Open AccessCell senescence is an antiviral defense mechanism
Cellular senescence is often considered a protection mechanism triggered by conditions that impose cellular stress. Continuous proliferation, DNA damaging agents or activated oncogenes are well-known activator...
