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    IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

    Macrophages are functionally highly plastic, but the transcriptional control of this process is only partially understood. Udalova and colleagues demonstrate that the transcription factor IRF5 controls the pla...

    Thomas Krausgruber, Katrina Blazek, Tim Smallie, Saba Alzabin… in Nature Immunology (2011)