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Integrated machine learning-based virtual screening and biological evaluation for identification of potential inhibitors against cathepsin K
Cathepsin K is a type of cysteine proteinase that is primarily expressed in osteoclasts and has a key role in the breakdown of bone matrix protein during bone resorption. Many studies suggest that the deficien...
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Article
Open AccessCalibration, validation and uncertainty analysis of a SWAT water quality model
Sediment and nutrient pollution in water bodies is threatening human health and the ecosystem, due to rapid land use changes and improper agricultural practices. The impact of the nonpoint source pollution nee...
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Article
Utilization of Corn Silk for GMO Detection Through Real-Time PCR
Corn silk is a fiber-rich byproduct obtained during corn processing. The present investigation deals with the purpose of GMO detection and quantification and comparison of DNA extraction in corn silk which is ...
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Article
28-Homo-Brassinolide Confers Cadmium Tolerance in Vigna radiate L. Through Modulating Minerals Uptake, Antioxidant System and Gas Exchange Attributes
Heavy metal stress is one of the most crucial abiotic factors that hamper plant growth and biomass production. Seed priming with brassinosteroids help plants to cope with a variety of abiotic stresses. The cur...
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Article
Open AccessInguinal lymph node metastases from rectal adenocarcinoma: a systematic review
Inguinal lymph nodes are a rare but recognised site of metastasis in rectal adenocarcinoma. No guideline or consensus exists for the management of such cases. This review aims to provide a contemporary and com...
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Open AccessPlant mediated fabrication of silver nanoparticles, process optimization, and impact on tomato plant
Nanotechnology is one of the fastest-growing markets, but develo** eco-friendly products, their maximum production, stability, and higher yield is a challenge. In this study, silver nanoparticles were synthe...
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Article
Glutathione Alleviates Chromium Stress and Promotes Growth of Pisum sativum L. by Improving Nutrient Orchestration, Proline, and Physiochemical Attributes
Chromium (Cr) pollution is one of the primary environmental concerns because of its adverse impact on crop productivity. Cr translocate in plants from the rhizosphere and enters the food chain, where it poses ...
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Exogenous application of glutathione enhanced growth, nutritional orchestration and physiochemical characteristics of Brassica oleracea L. under lead stress
A major obstacle to agricultural production and yield quality is heavy metal contamination of the soil and water, which leads to lower productivity and quality of crops. The situation has significantly worsene...
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Article
Ligand-based in silico identification and biological evaluation of potential inhibitors of nicotinamide N-methyltransferase
Nicotinamide N-methyltransferase (NNMT) is a protein coding gene, which methylates the nicotinamide (NA) (vitamin B3) to produce 1-methylnicotinamide (MNA). Several studies have suggested that the overexpression ...
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Article
Open AccessModeling the impacts of best management practices (BMPs) on pollution reduction in the Yarra River catchment, Australia
Pollution of a watershed by different land uses and agricultural practices is becoming a major challenging factor that results in deterioration of water quality affecting human health and ecosystems. Sustainab...
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Correction: Study of genetic modifications of flower development and methylation status in phytoplasma infected Brassica (Brassica rapa L.)
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Analysis of the Performance of YOLO Models for Tomato Plant Diseases Identification
Disease detection is an important task of field robotics for precision agriculture. Inspired by the deep learning model in performing high-level vision tasks, this research focused to identify models complexit...
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RGB to Multispectral Remap: A Cost-Effective Novel Approach to Recognize and Segment Plant Disease
Multispectral images represent radiant spectral energy captured at several light wavelengths; hence, these images are able to convey meaningful information related to the photon interactions. In agriculture, t...
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A New Methodology to Detect Plant Disease Using Reprojected Multispectral Images from RGB Colour Space
Plant disease detection is a pivotal step to prevent crop damage and maximise the crop yield. Although recent deep learning-based techniques achieved significant progress in this context, variations in plant a...
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Article
Study of genetic modifications of flower development and methylation status in phytoplasma infected Brassica (Brassica rapa L.)
The plants of B. rapa (syn. B. campestris) are the most important food crop of Pakistan for the production of cooking oil. Brassica plants infected by phytoplasma exhibit floral abnormalities including phyllody, ...
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Article
Simultaneous Colorimetric Sensing of Anion (I−) and Cation (Fe2+) by Protein Functionalized Silver Nanoparticles in Real Samples
Spherical shaped silver nanoparticles with the average size of 68.7 nm were synthesized from eco-friendly and environmentally safe approach using serum carrier protein 'fetuin-A' as stabilizing agent (named as...
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Article
Open AccessOptimization, purification and characterization of laccase from Ganoderma leucocontextum along with its phylogenetic relationship
The aim of this work to study an efficient laccase producing fungus Ganoderma leucocontextum, which was identified by ITS regions of DNA and phylogenetic tree was constructed. This study showed the laccase first-...
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Open AccessOptimum energy harvesting model for bidirectional cognitive radio networks
Wireless devices’ energy efficiency and spectrum shortage problem has become a key concern worldwide as the number of wireless devices increases at an unparalleled speed. Wireless energy harvesting technique f...
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Open AccessEffective implementation and adaptation of structured robotic colorectal programme in a busy tertiary unit
Safety and feasibility of robotic colorectal surgery has been reported as increasing over the last decade. However safe implementation and adaptation of such a programme with comparable morbidities and accepta...
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Physicochemical properties, bioactive compounds and total antioxidant activity of Blackberry (Syzygium cumini L.) juice retained by preservatives during storage
This study was conducted to analyze the impact of sodium benzoate (SB), potassium sorbate (PS), and citric acid (CA) on the physicochemical properties, bioactive components, antioxidant activity, and color of ...