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    Article

    RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia

    Many cases of AML are associated with mutational activation of receptor tyrosine kinases (RTKs) such as FLT3. However, RTK inhibitors have limited clinical efficacy as single agents, indicating that AML is dri...

    S. Rudat, A. Pfaus, Y. Y. Cheng, J. Holtmann, J. M. Ellegast, C. Bühler… in Leukemia (2018)