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Article
Open AccessIdiopathic erythrocytosis: a germline disease?
Polycythemia Vera (PV) is typically caused by V617F or exon 12 JAK2 mutations. Little is known about Polycythemia cases where no JAK2 variants can be detected, and no other causes identified. This condition is de...
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Article
Multiple scattering of channeled and non-channeled positively charged particles in bent monocrystalline silicon
We present the results of an experimental study of multiple scattering of positively charged high-energy particles in bent samples of monocrystalline silicon. This work confirms the recently discovered effect ...
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Article
Open AccessBeam-based aperture measurements with movable collimator jaws as performance booster of the CERN Large Hadron Collider
The beam aperture of a particle accelerator defines the clearance available for the circulating beams and is a parameter of paramount importance for the accelerator performance. At the CERN Large Hadron Collid...
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Article
Open AccessNonlinear dynamics of proton beams with hollow electron lens in the CERN high-luminosity LHC
The design stored beam energy in the CERN high-luminosity large hadron collider (HL-LHC) upgrade is about 700 MJ, with about 36 MJ in the beam tails, according to estimates based on scaling considerations from...
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Article
Open AccessFirst observation of ion beam channeling in bent crystals at multi-TeV energies
Planar channeling in bent crystals has been observed in LHC with multi-TeV proton beam in 2015. Two crystals, mounted on novel high-accuracy goniometers (one in the horizontal and one in the vertical plane), a...
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Article
Open AccessLayouts for fixed-target experiments and dipole moment measurements of short-lived baryons using bent crystals at the LHC
Several studies are on-going at CERN in the framework of the Physics Beyond Collider study group, with main aim of broadening the physics research spectrum using the available accelerator complex and infrastru...
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Accelerator Engineering and Technology: Accelerator Technology
Magnets are at the core of both circular and linear accelerators. The main function of a magnet is to guide the charged particle beam by virtue of the Lorentz force, given by the following expression:where q is t...
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Article
Open AccessFirst determination of the \({\rho }\) parameter at \({\sqrt{s} = 13}\) TeV: probing the existence of a colourless C-odd three-gluon compound state
The TOTEM experiment at the LHC has performed the first measurement at \(\sqrt{s} = 13\,\mathrm{TeV}\)s=13TeV of the \(\rho \)ρ parameter, the real to imaginary ratio of the nuclear elastic scattering amplitude a...
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Article
Open AccessDynamic Response of Advanced Materials Impacted by Particle Beams: The MultiMat Experiment
The introduction at CERN of new extremely energetic particle accelerators, such as the high-luminosity large hadron collider (HL-LHC) or the proposed future circular collider (FCC), will increase the energy st...
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Article
Open AccessFCC-hh: The Hadron Collider
In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC ...
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Article
Open AccessHE-LHC: The High-Energy Large Hadron Collider
In response to the 2013 Update of the European Strategy for Particle Physics (EPPSU), the Future Circular Collider (FCC) study was launched as a world-wide international collaboration hosted by CERN. The FCC ...
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Article
Open AccessFCC Physics Opportunities
We review the physics opportunities of the Future Circular Collider, covering its e+e-, pp, ep and heavy ion programmes. We describe the measurement capabilities of each FCC component, addressing the study of ele...
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Article
Open AccessFCC-ee: The Lepton Collider
In response to the 2013 Update of the European Strategy for Particle Physics, the Future Circular Collider (FCC) study was launched, as an international collaboration hosted by CERN. This study covers a highe...
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Article
Open AccessStudy of inelastic nuclear interactions of 400 GeV/c protons in bent silicon crystals for beam steering purposes
Inelastic nuclear interaction probability of 400 GeV/c protons interacting with bent silicon crystals was investigated, in particular for both types of crystals installed at the CERN Large Hadron Collider for ...
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Article
Open AccessDesign and implementation of a crystal collimation test stand at the Large Hadron Collider
Future upgrades of the CERN Large Hadron Collider (LHC) demand improved cleaning performance of its collimation system. Very efficient collimation is required during regular operations at high intensities, bec...
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Article
Open Access37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3)
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Open AccessMeasurement of elastic pp scattering at \(\sqrt{\hbox {s}} = \hbox {8}\) TeV in the Coulomb–nuclear interference region: determination of the \(\mathbf {\rho }\) -parameter and the total cross-section
The TOTEM experiment at the CERN LHC has measured elastic proton–proton scattering at the centre-of-mass energy \(\sqrt{s}=8\,\) ...
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Article
Comparative results on the deflection of positively and negatively charged particles by multiple volume reflections in a multi-strip silicon deflector
Bent silicon crystals in channeling mode are already used for beam extraction and collimation in particle accelerators. Volume reflection of beam particles is more efficient than beam channeling; however, the ...
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Article
Open AccessProlonged sedation in ARDS patients with inhaled anesthetics: our experience
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Article
BCR and BCR-ABL regulation during myeloid differentiation in healthy donors and in chronic phase/blast crisis CML patients
Chronic myeloid leukemia (CML) is caused by the BCR-ABL hybrid gene. The molecular mechanisms leading from chronic phase (CP) to blast crisis (BC) are not understood. However, both the presence and the levels ...
