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  1. Article

    Open Access

    Differential expression of RNA exosome subunits in the amphibian Lithobates catesbeianus during reproductive and non-reproductive periods

    The RNA exosome is an evolutionarily conserved 3′–5′ exoribonucleolytic protein complex involved in processing and degradation of different classes of nuclear and cytoplasmic RNAs, and, therefore, important fo...

    J. S. Luz, B. H. Caneguim, A. Baggio, M. M. Santoni, C. C. Helbing… in BMC Research Notes (2019)

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  2. Article

    Open Access

    Functionality and opposite roles of two interleukin 4 haplotypes in immune cells

    Cytokines expression can be influenced by polymorphisms in their respective coding genes. We associated the CTI/TTD haplotype (Hap-1) and TCI/CCI haplotype (Hap-2) in the IL4 gene formed by the −590, +33 and vari...

    G Anovazzi, M C Medeiros, S C Pigossi, L S Finoti, T M Souza Moreira… in Genes & Immunity (2017)

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  3. No Access

    Article

    Functional significance of eIF5A and its hypusine modification in eukaryotes

    The unusual basic amino acid, hypusine [Nε-(4-amino-2-hydroxybutyl)-lysine], is a modified lysine with the addition of the 4-aminobutyl moiety from the polyamine spermidine. This naturally occurring amino acid is...

    M. H. Park, K. Nishimura, C. F. Zanelli, S. R. Valentini in Amino Acids (2010)

  4. No Access

    Article

    Is there a role for eIF5A in translation?

    The putative translation factor eIF5A is essential for cell viability and is highly conserved from archaebacteria to mammals. This factor is the only cellular protein that undergoes an essential posttranslatio...

    C. F. Zanelli, S. R. Valentini in Amino Acids (2007)