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Article
Third Annual Huntington Disease Clinical Research Symposium
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Article
Inaugural Huntington Disease Clinical Research Symposium Organized by the Huntington Study Group
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Article
Analysis of the brain-stem white-matter tracts with diffusion tensor imaging
The authors have reviewed the diffusion tensor imaging (DTI) of the brain stem in 19 subjects, consisting of 15 normal volunteers and four multi-system atrophy patients. The study was performed with 1.5 T MRI ...
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Chapter
Role of CTL Mutants in Demyelination Induced by Mouse Hepatitis Virus, Strain JHM
Mouse hepatitis virus, strain JHM (MHV-JHM) is a well described cause of demyelination. C57B1/6 (B6) mice infected at the suckling stage in the presence of protective antibodies remain asymptomatic initially b...
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Chapter
Pathogenesis of Coronavirus-Induced Infections
Coronaviruses and arteriviruses infect multiple species of mammals, including humans, causing diseases that range from encephalitis to enteritis. Several of these viruses infect domestic animals and cause sign...
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Chapter
Spread of MHV-JHM from Nasal Cavity to White Matter of Spinal Cord
C57B1/6 mice infected intranasally with mouse hepatitis virus, strain JHM (MHV-JHM) develop hindlimb paralysis with histological evidence of demyelination several weeks after inoculation. Virus must spread fro...
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Chapter
Role of Macrophage Procoagulant Activity in Mouse Hepatitis Virus (MHV) Infection: Studies Using T Cell MHV-3 Clones and Monoclonal Antibody 3D4.3
Murine hepatitis virus strain 3 (MHV) infection produces a strain dependent spectrum of disease1,2. Mice of the A and SJL strain are fully resistant to the effects of viral infection, whereas mice of semisuscepti...
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Chapter
Dissemination of MHV4 (Strain JHM) Infection Does Not Require Specific Coronavirus Receptors
In this report, we demonstrate the syncytial spread of MHV4 (strain JHM) infection through non-murine cell cultures which lack a specific MHV4 receptor and are therefore resistant to infection by free virions....
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Chapter
Maternal Antibody-Modulated MHV-JHM Infection in C57BL/6 and BALB/c Mice
Mouse hepatitis virus, strain JHM, has proven to be a useful model for the study of viral persistence and latency. Several different clinical diseases are caused by this virus, dependent upon the age and route...
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Chapter and Conference Paper
Transcription and Translation in Mammalian Cells
In this report, we will consider several of the aspects of transcription and translation which are unique to eukaryotic cells. As our knowledge of the macromolecular biochemistry of higher organisms grows, it ...
