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  1. Article

    Open Access

    TGFβ-induced cytoskeletal remodeling mediates elevation of cell stiffness and invasiveness in NSCLC

    Importance of growth factor (GF) signaling in cancer progression is widely acknowledged. Transforming growth factor beta (TGFβ) is known to play a key role in epithelial-to-mesenchymal transition (EMT) and met...

    E. Gladilin, S. Ohse, M. Boerries, H. Busch, C. Xu, M. Schneider in Scientific Reports (2019)

  2. Article

    Open Access

    Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response

    In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined ph...

    D. Dvornikov, M. A. Schneider, S. Ohse, M. Szczygieł, I. Titkova in Scientific Reports (2018)