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  1. No Access

    Article

    Changes in concentrations of methylglyoxal,d-lactate and glyoxalase activities in liver and plasma of rats fed a 3′-methyl-4-dimethylaminoazobenzene-rich diet

    Donryu male albino rats were fed a diet containing 0.064% 3′-methyl-4-dimethylaminoazobenzene (MDAB) for 21 weeks. During the ensuing rat liver carcinogenesis, changes in the concentrations of methylglyoxal,d-lac...

    M. Kawase, M. Tada, S. Akagi, S. Ohmori in Research in Experimental Medicine (1996)

  2. No Access

    Article

    Changes in levels of glutathione and related compounds and activities of glutathione-related enzymes during rat liver regeneration

    The levels of glutathione and glutathione disulfide increased during the regeneration process of rat liver, reaching a maximum (about twice the control value) on day 2 and reverting to the normal level within ...

    M. Teshigawara, S. Matsumoto, S. Tsuboi, S. Ohmori in Research in Experimental Medicine (1995)

  3. Article

    The association of the insulin resistance syndrome with impaired glucose tolerance and NIDDM in the Japanese general population: the Hisayama study

    To elucidate the risk factors for initiating glucose intolerance, the relevant factors were explored in a cross-sectional survey conducted in a sample population aged 40–79 years old selected from a Japanese c...

    Dr. T. Ohmura, K. Ueda, Y. Kiyohara, I. Kato, H. Iwamoto, K. Nakayama… in Diabetologia (1994)

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  4. Article

    Prevalence of Type 2 (non-insulin-dependent) diabetes mellitus and impaired glucose tolerance in the Japanese general population: the Hisayama study

    We determined the population-based prevalence of diabetes mellitus in members of the Japanese community, Hisayama aged 40–79 years old by a 75-g oral glucose tolerance test. The basic population used to calcul...

    T. Ohmura, K. Ueda, Y. Kiyohara, I. Kato, H. Iwamoto, K. Nakayama… in Diabetologia (1993)

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  5. No Access

    Article

    Increase ofS-(1,2-dicarboxyethyl)glutathione in regenerating rat liver

    Changes in the level ofS-(1,2-dicarboxyethyl)glutathione (DCE-GS) with time were determined during regeneration of rat liver after partial hepatectomy. The DCE-GS level increased in regenerating rat liver, reachi...

    S. Tsuboi, M. Miyazaki, Y. Kondo, K. Kiyono… in Research in Experimental Medicine (1992)

  6. No Access

    Article

    Concentrations ofd-lactate and its related metabolic intermediates in liver, blood, and muscle of diabetic and starved rats

    This is a report investigating the methylglyoxal (MG) bypass in animals, by whichd-lactate is produced from triosephosphate via MG. Rats were made diabetic using streptozotocin or starved for 72 h.d-Lactate and v...

    Y. Kondoh, M. Kawase, Y. Kawakami, S. Ohmori in Research in Experimental Medicine (1992)

  7. No Access

    Article

    Enhancing effect of S-(1,2-dicarboxyethyl)glutathione on epidermal growth factor-stimulated DNA synthesis in primary cultures of adult rat hepatocytes

    A tripeptide S-(1,2-dicarboxyethyl)glutathione (DCE-GS) has been reported to be present in the lens, liver, and heart. Effects of DCE-GS and its derivatives and analogues on hepatocyte deoxyribonucleic acid (DNA)...

    M. Miyazaki, L. Bai, S. Tsuboi, S. Ohmori, K. Ogata… in Research in Experimental Medicine (1990)