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    Article

    Rostral-Caudal Hippocampal Functional Convergence Is Reduced Across the Alzheimer’s Disease Spectrum

    Beginning in the early stages of Alzheimer’s disease (AD), the hippocampus reduces its functional connections to other cortical regions due to synaptic depletion. However, little is known regarding connectivit...

    Joseph Therriault, S. Wang, S. Mathotaarachchi in Molecular Neurobiology (2019)

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    Open Access

    Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease

    This study was designed to test the interaction between amyloid-β and tau proteins as a determinant of metabolic decline in preclinical Alzheimer’s disease (AD). We assessed 120 cognitively normal individuals ...

    T A Pascoal, S Mathotaarachchi, S Mohades, A L Benedet, C-O Chung in Molecular Psychiatry (2017)