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  1. No Access

    Article

    Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans

    Multiple sclerosis (MS) is a common disease of the central nervous system characterized by inflammation, myelin loss, gliosis, varying degrees of axonal pathology, and progressive neurological dysfunction. Mul...

    D Brassat, A A Motsinger, S J Caillier, H A Erlich, K Walker… in Genes & Immunity (2006)

  2. No Access

    Article

    The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2–3

    The proteases of the lectin pathway of complement activation, MASP-1 and MASP-2, are encoded by two separate genes. The MASP1 gene is located on chromosome 3q27, the MASP2 gene on chromosome 1p36.23–31. The ge...

    C Stover, Y Endo, M Takahashi, NJ Lynch, C Constantinescu… in Genes & Immunity (2001)

  3. No Access

    Article

    A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX2)

    R. Huff, P. Collins, S. Kramer, K. Seibert, C. Koboldt, S. Gregory… in Inflammation Research (1995)