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  1. No Access

    Article

    Isolated tumefactive demyelinating lesions: diagnosis and long-term evolution of 16 patients in a multicentric study

    Isolated tumefactive demyelinating lesion (TDL) is a rare disease and a challenging entity especially for the differential diagnosis, biopsy indications, and therapeutic decisions. Long-term evolution is not w...

    A. Siri, Clarisse Carra-Dalliere, X. Ayrignac, J. Pelletier… in Journal of Neurology (2015)

  2. No Access

    Article

    HLA-DRB1*15 allele influences the later course of relapsing remitting multiple sclerosis

    Most of the published works so far have aimed at finding genes associated with multiple sclerosis (MS) susceptibility. Very few studies have attempted to correlate disease features with DNA variants. In a well...

    I Cournu-Rebeix, E Génin, E Leray, M-C Babron, J Cohen, C Gout… in Genes & Immunity (2008)

  3. No Access

    Article

    IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations

    Multiple sclerosis (MS) is the most common chronic inflammatory neurologic disorder diagnosed in young adults and, due to its chronic course, is responsible for a substantial economic burden. MS is considered ...

    F Weber, B Fontaine, I Cournu-Rebeix, A Kroner, M Knop, S Lutz… in Genes & Immunity (2008)

  4. No Access

    Article

    Multifactor dimensionality reduction reveals gene–gene interactions associated with multiple sclerosis susceptibility in African Americans

    Multiple sclerosis (MS) is a common disease of the central nervous system characterized by inflammation, myelin loss, gliosis, varying degrees of axonal pathology, and progressive neurological dysfunction. Mul...

    D Brassat, A A Motsinger, S J Caillier, H A Erlich, K Walker… in Genes & Immunity (2006)

  5. No Access

    Chapter

    Epidemiologie und Genetik

    Wie bei den meisten Autoimmunkrankheiten scheinen eine genetische Prä-disposition und Umweltfaktoren notwendig zu sein, damit eine multiple Sklerose entstehen kann. Ungewiss bleibt jedoch, wie stark sich die g...

    M. Clanet, B. Fontaine, C. Azais-Vuillemin, D. Brassat in Demyelinisierende Erkrankungen (2003)