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Open AccessAuthor Correction: Universal DNA methylation age across mammalian tissues
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Open AccessUniversal DNA methylation age across mammalian tissues
Aging, often considered a result of random cellular damage, can be accurately estimated using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we demonstrate the development of u...
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Successful combination therapy using adalimumab and 5-aminosalicylic acid for a resistant case of intestinal Behçet’s disease
Behçet’s disease (BD) is a recurrent, multisystemic, inflammatory blood vessel disorder that can result in mouth, genital, and skin ulcers; arthritis; and eye and intestinal inflammation. We describe a 21-year...
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First Asian case of biopsy-confirmed manubriosternal joint involvement in rheumatoid arthritis
Rheumatoid arthritis (RA) is an inflammatory polyarthritis that typically affects the small joints but can also involve the manubriosternal joint (MSJ). Although cases of MSJ involvement in RA are rare, such c...
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Article
Increased Productivity and Antifreeze Activity of Ice-binding Protein from Flavobacterium frigoris PS1 Produced using Escherichia coli as Bioreactor
Ice-binding proteins (IBPs) inhibit the growth and recrystallization of intracellular ice, enabling polar organisms to survive at subzero temperatures. IBPs are promising materials in biomedical applications s...
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EuroQol Visual Analogue Scale (EQ-VAS) as a Predicting Tool for Frailty in Older Korean Adults: The Korean Frailty and Aging Cohort Study (KFACS)
This study was conducted to determine the cutoff value and efficacy of the EuroQol Visual Analogue Scale (EQ-VAS) for predicting frailty.
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Laser surface modification of Ti and TiC coatings on magnesium alloy
In order to enhance the surface properties of magnesium alloy, a highly intense laser surface melting process following plasma spraying of Ti or TiC on AZ31 alloy were employed. When laser surface melting was ...
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Article
Parallel model based fault detection algorithm for electronic parking brake system
This paper describes a parallel model-based fault detection algorithm for an electronic parking brake (EPB) system, which consists of an electronic control unit with built-in current sensor and braking force s...
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Apparent treatment-resistant hypertension among elderly Korean hypertensives: an insight from the HIT registry
The aim of this study was to determine the clinical characteristics of patients with resistant hypertension (RH) and predictors among elderly Korean hypertensives. This prospective, multi-center, observational...
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Assessing the Stability of a Geologically Complex Slope Where Strong Dykes Locally Act as Reinforcement
This paper presents a case study of aspects of the design of large slope cuttings in complex geological conditions in South Korea. During the original cutting of the slopes to geometries prescribed by Korean s...
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Additive association of vitamin D insufficiency and sarcopenia with low femoral bone mineral density in noninstitutionalized elderly population: the Korea National Health and Nutrition Examination Surveys 2009–2010
Vitamin D insufficiency and sarcopenia are crucial risk factors for osteoporosis. In a study of noninstitutionalized elderly subjects, we investigated the simultaneous effect of vitamin D and sarcopenia on bon...
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A compartment model with variable ion channel density on the propagation of action potentials along a nonuniform axon
The transmission of a signal through an axon is studied using a compartment model of a non-uniform axon. We find that the transmission efficiency in these axons has nonlinear mode-locking structure that depend...
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Cloning of a Family 11 Xylanase Gene from Bacillus amyloliquefaciens CH51 Isolated from Cheonggukjang
Bacillus amyloliquefaciens CH51, an isolate from cheonggukjang, Korean fermented soyfood, secretes several enzymes into culture medium. A gene encoding 19 kDa xylanase was cloned by PCR. Sequenci...
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Open AccessSheeting Joints: Characterisation, Shear Strength and Engineering
Sheeting joints are extensive fractures that typically develop parallel to natural slopes. Embryonic sheeting joints initially constitute channels for water flow and then become the focus for weathering and se...
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Inhibition of AP-1 by SARI negatively regulates transformation progression mediated by CCN1
Enhanced expression of the CCN family of secretory integrin-binding proteins correlates with many essential components of the cancerous state, including tumor cell adhesion, proliferation, invasion and migrati...
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Article
Quantitative determination of scratch-induced damage visibility on polymer surfaces
A new methodology to quantify scratch-induced damage visibility on polymer surfaces is proposed. The color image analysis using a hue–saturation–intensity (HSI) color space combination provides satisfactory re...
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The effect of anti-tumor necrosis factor agents on sexual dysfunction in male patients with ankylosing spondylitis: a pilot study
Sexual dysfunction is a common problem among patients with ankylosing spondylitis (AS). This study was an open-label study without placebo to assess sexual dysfunction in male patients with AS, and to determin...
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Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma
Neuroblastoma, derived from neural crest progenitor cells, is the most common extracranial solid tumor of childhood. Astrocyte elevated gene-1 (AEG-1) is a primary mediator of tumor progression and metastasis ...
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Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling
Astrocyte elevated gene-1 (AEG-1) displays oncogenic properties. Its expression is elevated in diverse neoplastic states and it cooperates with Ha-ras to promote cellular transformation. Overexpression of AEG-...
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Article
DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-κB
Mast cell-mediated allergic inflammation is involved in many diseases such as asthma, sinusitis, and rheumatoid arthritis. Mast cells induce synthesis and production of pro-inflammatory cytokines including tum...
