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  1. No Access

    Article

    Activation of the Cannabinoid Receptors Suppresses Hyperexcitation of Rat Hippocampal Neuronal Networks In Vitro

    Cannabinoid receptors (CBRs) play a key role in various physiological processes, including neurogenesis, synaptic plasticity, immune modulation, cell apoptosis, metabolism regulation, cardiovascular and reprod...

    S. A. Maiorov, B. K. Kairat, S. G. Gaidin… in Biochemistry (Moscow), Supplement Series A… (2023)

  2. Article

    Open Access

    BDNF Overexpression Enhances the Preconditioning Effect of Brief Episodes of Hypoxia, Promoting Survival of GABAergic Neurons

    Hypoxia causes depression of synaptic plasticity, hyperexcitation of neuronal networks, and the death of specific populations of neurons. However, brief episodes of hypoxia can promote the adaptation of cells....

    M. V. Turovskaya, S. G. Gaidin, M. V. Vedunova, A. A. Babaev… in Neuroscience Bulletin (2020)

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  3. No Access

    Article

    Visualization, Properties, and Functions of GABAergic Hippocampal Neurons Containing Calcium-Permeable Kainate and AMPA Receptors

    Calcium-permeable kainate (CP-KARs) and AMPA (CP-AMPARs) receptors of the brain neurons are active participants of synaptic plasticity and neurotransmitter release trigger. In this paper, CP-KARs and CP-AMPARs...

    V. P. Zinchenko, S. G. Gaidin, I. Yu. Teplov… in Biochemistry (Moscow), Supplement Series A… (2020)

  4. No Access

    Article

    A Complex Neuroprotective Effect of Alpha-2-Adrenergic Receptor Agonists in a Model of Cerebral Ischemia–Reoxygenation In Vitro

    The mechanism of the neuroprotective action of α2-adrenergic receptor agonists in a model of oxygen-glucose deprivation (OGD) in vitro was investigated. Using fluorescent microscopy, immunostaining, inhibitor ana...

    S. G. Gaidin, M. V. Turovskaya… in Biochemistry (Moscow), Supplement Series A… (2019)

  5. No Access

    Article

    The Influence of Simple Phenols on Collagen Type I Fibrillogenesis in vitro

    The influence of phenolic compounds with different numbers of hydroxy groups (phenol, pyrocatechol, resorcinol, and pyrogallol) on the kinetics of in vitro fibrillogenesis of collagen and on fibril structure h...

    Yu. A. Kim, S. G. Gaidin, Yu. S. Tarahovsky in Biophysics (2018)

  6. No Access

    Article

    Calcium-Binding Proteins Protect GABAergic Neurons of the Hippocampus from Hypoxia and Ischemia in vitro

    Disturbances in cerebral blood flow cause hypoxic and ischemic processes that lead to damaging and death of neurons. Some populations of GABAergic neurons are characterized by greater sensitivity to oxygen-glu...

    E. A. Turovsky, V. P. Zinchenko… in Biochemistry (Moscow), Supplement Series A… (2018)

  7. No Access

    Article

    Inhibition of spontaneous synchronous activity of hippocampal neurons by excitation of GABAergic neurons

    The molecular mechanisms of the neuronal spontaneous synchronous activity (SSA) regulation by population of GABAergic neurons have been investigated in rat hippocampal culture. The neurons from this population...

    V. P. Zinchenko, S. G. Gaidin, I. Y. Teplov… in Biochemistry (Moscow), Supplement Series A… (2017)