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Article
Open AccessMultivesicular exocytosis in rat pancreatic beta cells
To establish the occurrence, modulation and functional significance of compound exocytosis in insulin-secreting beta cells.
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Article
Open AccessLong-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon
Long-term exposure to NEFAs leads to inhibition of glucose-induced insulin secretion. We tested whether the release of somatostatin and glucagon, the two other major islet hormones, is also affected.
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Article
Open AccessAdiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations
Adiponectin is an adipokine with insulin-sensitising and anti-atherogenic properties. Several reports suggest that genetic variants in the adiponectin gene are associated with circulating levels of adiponectin...
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Article
Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8
Genetic investigations in the spontaneously diabetic (Type 2) Goto Kakizaki (GK) rat have identified quantitative trait loci (QTL) for diabetes-related phenotypes. The aims of this study were to refine the chr...
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Article
35th Annual Meeting of the European Association for the Study of Diabetes
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Chapter and Conference Paper
Multi-dimensional Power Spectral Analysis of Structure in the Stratosphere and Mesosphere Observed by Rayleigh Scatter Lidar
The spatial and temporal distributions of density structure in the upper stratosphere and lower mesosphere (40 to 80 km altitude) are observed by Rayleigh scatter lidar at USU. We utilize advanced two dimensio...
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Chapter and Conference Paper
The Alexandrite Ring Laser: A Spectrally Narrow Lidar Light Source for Atmospheric Fluorescence and Absorption Observations
The Atmospheric Lidar Observatory (ALO) at Utah State University has recently acquired an alexandrite laser, developed by Light Age Incorporated, that is a relatively new type of configuration, ideal for reson...
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Chapter and Conference Paper
Climatology of Mesospheric Temperature Profiles Observed with the Consortium Rayleigh-Scatter Lidarat Logan, Utah
From Aug. 1993 to Feb. 1996, regular Rayleigh-scatter observations of the stratosphere and mesosphere in the altitude range 40–95 km were made with the Consortium Lidar (CL) located at Utah State University. T...
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Chapter
Hydraulically Operated Two-Phase Helium Expansion Engine
Traditional helium refrigerators and liquefiers have generally contained two or three stages of refrigeration; namely, liquid-nitrogen precooling, one or two reciprocating expansion engines or turbine expander...
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Chapter and Conference Paper
Helium Refrigerator and Liquefier
An investigation at the Massachusetts Institute of Technology, sponsored by the Bureau of Ordnance and later by the Office of Naval Research, of the feasibility of the liquefaction of hydrogen by condensation ...
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Chapter and Conference Paper
Hydrogen-Helium Liquefier
Experience over the last four years with a fairly large helium liquéfier led to the belief that it would be possible to reduce the cost per liter of liquefying helium and hydrogen to a figure only slightly gre...
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Chapter and Conference Paper
Design and Performance Data on a Laboratory Size Liquid Nitrogen Plant
The need for a simple laboratory size liquid nitrogen generator is increasing rapidly as more and more organizations enter the cryogenic field, and research efforts in low-temperature applications increase. Ar...
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Chapter
Helium Liquefiers and Carriers
The initial interest in very low temperatures was created chiefly by the desire to liquefy the so-called permanent gases. Hydrogen was first liquefied in 1898 but ten years passed before Kamerlingh-Onnes and his ...