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  1. Article

    Open Access

    The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis

    Mitochondrial topoisomerase IB (TOP1MT) is a nuclear-encoded topoisomerase, exclusively localized to mitochondria, which resolves topological stress generated during mtDNA replication and transcription. Here, ...

    S. A. Baechler, V. M. Factor, I. Dalla Rosa, A. Ravji, D. Becker… in Nature Communications (2019)

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