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Article
Da Vinci SP robotic approach to colorectal surgery: two specific indications and short-term results
Da Vinci® Single Port (dvSP) was recently developed. Its application in colorectal surgery is under investigation. The aim of this study was to explore the safety and feasibility of dvSP for intersphincteric (...
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Article
Particle Detector (PD) Experiment of the Korea Space Environment Monitor (KSEM) Aboard Geostationary Satellite GK2A
The Particle Detector (PD) experiment aboard the geostationary satellite GEO-KOMPSAT-2A (GK2A) measures populations of electrons and positive ions in the Earth’s geostationary orbit at a geographic longitude of 1...
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Article
Monitoring rate and predictability of intraoperative monitoring in patients with intradural extramedullary and epidural metastatic spinal tumors
Single-center retrospective study.
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Article
Dynamic prognostic value of the revised international prognostic scoring system following pretransplant hypomethylating treatment in myelodysplastic syndrome
This study aimed to analyze the use of the revised International Prognostic Scoring System (IPSS-R) assessed after hypomethylating treatment (HMT) for patients with myelodysplastic syndrome (MDS) undergoing an...
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Article
Comparable outcomes between younger (⩽40 years) and older (>40 years) adult patients with severe aplastic anemia after HLA-matched sibling stem cell transplantation using fludarabine-based conditioning
Allogeneic stem cell transplantation from HLA-matched siblings (MSD-SCT) for elderly patients with severe aplastic anemia (SAA) is not a widely accepted first-line treatment. Recently, fludarabine, lower-dose ...
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Article
Open AccessHOI-02 induces apoptosis and G2-M arrest in esophageal cancer mediated by ROS
Reactive oxygen species (ROS) are chemically reactive molecules that perform essential functions in living organisms. Accumulating evidence suggests that many types of cancer cells exhibit elevated levels of R...
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Article
Mutation in TET2 or TP53 predicts poor survival in patients with myelodysplastic syndrome receiving hypomethylating treatment or stem cell transplantation
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Article
Long-term outcome of transanal irrigation for children with spina bifida
Experimental, prospective study.
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Article
Impact of IKZF1 deletions on long-term outcomes of allo-SCT following imatinib-based chemotherapy in adult Philadelphia chromosome-positive ALL
We investigated the prognostic relevance of IKZF1 deletions in 118 adult Ph-positive ALL patients who had minimal residual disease (MRD) data under a uniform treatment of allo-SCT following first-line imatinib-ba...
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Article
Identification of molecular and cytogenetic risk factors for unfavorable core-binding factor-positive adult AML with post-remission treatment outcome analysis including transplantation
Emerging molecular studies have identified a subgroup of patients with unfavorable core-binding factor-positive (CBF)-AML who should be treated by intensified post-remission treatments. We analyzed 264 adults ...
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Article
Open AccessArrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A
Methionine sulfoxide reductase A (MSRA) protects proteins from oxidation, and also helps remove reactive oxygen species (ROS) by recovering antioxidant enzymes inactivated by oxidation. Although its functions ...
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Article
PBSC vs BM grafts with myeloablative conditioning for unrelated donor transplantation in adults with high-risk ALL
Few studies are available that compare PBSC and BM from unrelated donors, especially in adult high-risk ALL. To determine which graft source is superior in adult high-risk ALL, we analyzed the long-term outcom...
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Article
Experiences of t-PA use in moderate-to-severe hepatic veno-occlusive disease after hematopoietic SCT: is it still reasonable to use t-PA?
Hepatic veno-occlusive disease (VOD) remains one of the most severe complications of hematopoietic SCT (HSCT). Anticoagulation and thrombolytic therapies using tissue-plasminogen activator (t-PA) have been use...
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Article
Beam optics correction in the PLS-II storage ring
LOCO (Linear Optics from Closed Orbit) is a tool to analyze linear beam-optics and search for errors in the quadrupole focusing strength. Analysis with the help of LOCO reveals these errors by fitting the meas...
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Article
A randomized, multi-center, open-label, phase II study of once-per-cycle DA-3031, a biosimilar pegylated G-CSF, compared with daily filgrastim in patients receiving TAC chemotherapy for early-stage breast cancer
Backgrounds A pegylated form of recombinant granulocyte-colony stimulating factor (G-CSF) was developed for prophylactic use in breast cancer. The aim of this study was to evaluate the efficacy and safety of onc...
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Article
Survival benefits with transplantation in secondary AML evolving from myelodysplastic syndrome with hypomethylating treatment failure
The prognosis for patients with myelodysplastic syndrome with hypomethylating treatment failure (MDS-HTF) has been known to be poor. However, the clinical outcomes and optimal treatment options for secondary A...
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Article
The effects of transanal irrigation as a stepwise bowel management program on the quality of life of children with spina bifida and their caregivers
Experimental, prospective study.
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Article
Risk and prognostic factors for acute GVHD based on NIH consensus criteria
To investigate the risk factors for acute GVHD (aGVHD), based on NIH consensus criteria (NCC), we evaluated 775 patients who underwent allogeneic transplantation. Of them, 346 patients developed aGVHD by NCC, ...
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Article
Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor
To investigate the inhibitory effect of cocoa polyphenol extract (CPE) on adipogenesis and obesity along with its mechanism of action.
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Article
Impact of minimal residual disease kinetics during imatinib-based treatment on transplantation outcome in Philadelphia chromosome-positive acute lymphoblastic leukemia
We conducted a systemic evaluation to describe the effect of minimal residual disease (MRD) kinetics on long-term allogeneic transplantation outcome by analyzing 95 adult transplants with Philadelphia chromoso...