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Open AccessProper understanding of recurrent stress urinary incontinence treatment in women (PURSUIT): a randomised controlled trial of endoscopic and surgical treatment
Women with stress urinary incontinence (SUI) experience urine leakage with physical activity. Currently, the interventional treatments for SUI are surgical, or endoscopic bulking injection(s). However, these p...
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Open AccessModelling the lifetime cost-effectiveness of radical prostatectomy, radiotherapy and active monitoring for men with clinically localised prostate cancer from median 10-year outcomes in the ProtecT randomised trial
Optimal management strategies for clinically localised prostate cancer are debated. Using median 10-year data from the largest randomised controlled trial to date (ProtecT), the lifetime cost-effectiveness of ...
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Open AccessUrodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM) for diagnosis and management of bladder outlet obstruction in men: study protocol for a randomised controlled trial
Lower urinary tract symptoms (LUTS) comprise storage symptoms, voiding symptoms and post-voiding symptoms. Prevalence and severity of LUTS increase with age and the progressive increase in the aged population ...
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Open AccessRadiation overdose: the utility of ct scanning in self poisoning
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Open AccessDesign and preliminary recruitment results of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)
Screening for prostate cancer continues to generate controversy because of concerns about over-diagnosis and unnecessary treatment. We describe the rationale, design and recruitment of the Cluster randomised t...
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Open AccessHaemoglobin concentration on admission to intensive care influences hospital mortality rates and length of stay: a retrospective study
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Application of teledentistry in oral medicine in a Community Dental Service, N. Ireland
Presents a pilot series of patients with oral mucosal problems who had high quality clinical photography of their lesions taken in primary care and then viewed...
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Glycaemic status influences the nature and severity of coronary artery disease
We sought to understand the relationships between glycaemic status and both severity and progression of coronary artery disease (CAD), the leading cause of death in diabetes.
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Open AccessEpidemiology and pathophysiology of cancer-associated thrombosis
Venous thromboembolism (VTE) is a common complication in patients with malignant disease. First recognised by Bouillard in 1823 and later described by Trousseau in 1844, multiple studies have since provided co...
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Platelet count as a prognostic marker in intensive care
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Open AccessEvaluation of ER, PgR, HER-2 and Ki-67 as predictors of response to neoadjuvant anthracycline chemotherapy for operable breast cancer
Primary systemic therapy (PST) for operable breast cancer enables the identification of in vivo biological markers that predict response to treatment. A total of 118 patients with T2–4 N0–1 M0 primary breast canc...
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Food and nutrient intake in a cohort of 8-month-old infants in the south-west of England in 1993
Objective: To investigate food and nutrient intakes in 8-month-old infants.
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Erratum to: Ticlopidine: a review of its pharmacology clinical efficacy and tolerability in the prevention of cerebral ischaemia and stroke
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Erratum to Sulfasalazine: a review of its pharmacological properties and therapeutic efficacy in the treatment of rheumatoid arthritis