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  1. No Access

    Article

    Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum

    Intranasal application of dopamine (IN-DA) has been shown to increase motor activity and to release DA in the ventral (VS) and dorsal striatum (DS) of rats. The aim of the present study was to assess the effec...

    L. A. Ruocco, C. Treno, U. A. Gironi Carnevale, C. Arra, C. Mattern… in Amino Acids (2014)

  2. No Access

    Article

    Examination of the current top candidate genes for AD in a genome-wide association study

    With the advent of technologies that allow simultaneous genoty** of thousands of single-nucleotide polymorphisms (SNPs) across the genome, the genetic contributions to complex diseases can be explored at an ...

    T M Feulner, S M Laws, P Friedrich, S Wagenpfeil, S H R Wurst… in Molecular Psychiatry (2010)

  3. No Access

    Article

    From model cell line to in vivo gene expression: disease-related intestinal gene expression in IBD

    Crohn's disease (CD) and ulcerative colitis (UC) are subforms of inflammatory bowel diseases (IBD). Genetic and environmental factors influencing the onset and course of the diseases have been recently identif...

    H A Schulze, R Häsler, N Mah, T Lu, S Nikolaus, C M Costello… in Genes & Immunity (2008)

  4. No Access

    Article

    Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes

    Immunosenescence is characterized by a quantitative decline of adequate immune responses, which renders the elderly individual particularly susceptible to bacterial, viral and fungal pathogens. Whereas changes...

    P Rosenstiel, S Derer, A Till, R Häsler, H Eberstein, B Bewig… in Genes & Immunity (2008)

  5. No Access

    Article

    In vivo snapshots of the dopaminergic synapse in small animals

    S Nikolaus, M Beu, A Wirrwar, C Antke, H-W Müller in Molecular Psychiatry (2005)

  6. No Access

    Article

    Definition of polymorphisms and haplotypes in the interleukin-12B gene: association with IL-12 production but not with Crohn's disease

    Interleukin-12 (IL-12) is a key cytokine for the induction of Th1 immune responses. Recently, functional polymorphisms in IL-12p40 (IL12B) were found to be associated with susceptibility to several autoimmune dis...

    A Zwiers, D Seegers, R Heijmans, A Koch, J Hampe, S Nikolaus, A S Peña… in Genes & Immunity (2004)